{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:36:39Z","timestamp":1774535799683,"version":"3.50.1"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2013,5,2]],"date-time":"2013-05-02T00:00:00Z","timestamp":1367452800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215113000923_sec1\"><jats:title>Objective:<\/jats:title><jats:p>This study aimed to investigate the computed tomography and magnetic resonance imaging findings of primary middle-ear carcinoma.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000923_sec2\"><jats:title>Methods:<\/jats:title><jats:p>In this retrospective study of 13 patients with primary middle-ear carcinoma, we collected pre- and post-contrast magnetic resonance images for all 13 cases, high-resolution computed tomography scans for 11 cases, and conventional computed tomography scans with contrast for 2 cases.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000923_sec3\"><jats:title>Results:<\/jats:title><jats:p>Soft-tissue masses were mainly located in the tympanum, tympanic sinus and deep within the external auditory canal, and involved the jugular fossa (9 of 13 patients), middle cranial fossa (5\/13), parotid gland (2\/13) and temporomandibular joint fossa (1\/13). An irregular, \u2018moth-eaten\u2019 bone destruction pattern was seen on high-resolution computed tomography images, most commonly in the eustachian tube (9\/13), jugular foramen (9\/13) and facial nerve canal (7\/13). On non-contrast magnetic resonances images, masses were isointense or slightly hypointense on T1-weighted images, and isointense or slightly hyperintense on T2-weighted images. On post-contrast images, lesions were moderately and homogeneously enhanced in seven cases and inhomogeneously enhanced in six.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000923_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>High-resolution computed tomography precisely detects regions of bone destruction, whereas MRI can better assess soft-tissue tumour margins, intracranial extension and vessel patency. Eustachian tube erosion is an important characteristic of primary middle-ear carcinoma.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215113000923","type":"journal-article","created":{"date-parts":[[2013,5,2]],"date-time":"2013-05-02T17:13:18Z","timestamp":1367514798000},"page":"578-583","source":"Crossref","is-referenced-by-count":13,"title":["Computed tomography and magnetic resonance imaging findings for primary middle-ear carcinoma"],"prefix":"10.1017","volume":"127","author":[{"given":"F","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Sha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,5,2]]},"reference":[{"key":"S0022215113000923_ref8","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100109624"},{"key":"S0022215113000923_ref7","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1002\/lary.20937","article-title":"Squamous cell carcinoma of the temporal bone","volume":"120","author":"Gidley","year":"2010","journal-title":"Laryngoscope"},{"key":"S0022215113000923_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20877"},{"key":"S0022215113000923_ref1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20202"},{"key":"S0022215113000923_ref12","first-page":"45","article-title":"Diagnosis and evaluation of head and neck paragangliomas. Computed tomography and magnetic resonance imaging [in Spanish]","volume":"60","author":"Paniagua Escudero","year":"2009","journal-title":"Acta Otorrinolaringol Esp"},{"key":"S0022215113000923_ref2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2002.02313.x"},{"key":"S0022215113000923_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2005.11.012"},{"key":"S0022215113000923_ref9","doi-asserted-by":"publisher","DOI":"10.1177\/000348946507400222"},{"key":"S0022215113000923_ref11","first-page":"21","article-title":"Histopathological studies of intratemporal growth behavior of middle ear carcinoma [in German]","volume":"79","author":"Ussm\u00fcller","year":"2000","journal-title":"Laryngorhinootologie"},{"key":"S0022215113000923_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-005-2743-8"},{"key":"S0022215113000923_ref6","first-page":"582","article-title":"Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system","volume":"21","author":"Moody","year":"2000","journal-title":"Am J Otol"},{"key":"S0022215113000923_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181a14b99"},{"key":"S0022215113000923_ref5","first-page":"600","article-title":"Clinical analysis of 20 cases of carcinoma of the middle ear [in Chinese]","volume":"17","author":"Wang","year":"2003","journal-title":"Lin Chuang Er Bi Yan Hou Ke Za Zhi"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215113000923","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T00:15:54Z","timestamp":1715300154000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215113000923\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,2]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["S0022215113000923"],"URL":"https:\/\/doi.org\/10.1017\/s0022215113000923","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,2]]}}}