{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:36:56Z","timestamp":1789691816303,"version":"4.0.1"},"reference-count":31,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2013,6,13]],"date-time":"2013-06-13T00:00:00Z","timestamp":1371081600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215113001230_sec1\"><jats:title>Objective:<\/jats:title><jats:p>To present the first case of middle-ear actinomycosis in the UK in the last 60 years. The diagnosis and management of actinomycosis of the middle ear is also presented, as well as a review of the recent literature.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113001230_sec2\"><jats:title>Case report:<\/jats:title><jats:p>This paper reports the case of a nine-year-old girl who presented with recurrent otorrhoea caused by actinomycosis. Mastoid exploration with clearance of the infected tissue, in conjunction with six months amoxicillin, resulted in long-term disease remission. Histology revealed Gram-positive, silver avid (on Grocott staining) and diastase-resistant periodic acid-Schiff negative staining of colonies; this profile was in keeping with the characteristic \u2018sulphur granules\u2019 of actinomycosis.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113001230_sec3\"><jats:title>Conclusion:<\/jats:title><jats:p>Actinomycosis of the middle ear and mastoid is rare, with less than 45 cases presented in the worldwide literature. This case confirms that the disease should be treated with full surgical clearance and long-term antibiotics.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215113001230","type":"journal-article","created":{"date-parts":[[2013,6,13]],"date-time":"2013-06-13T08:40:23Z","timestamp":1371112823000},"page":"712-715","source":"Crossref","is-referenced-by-count":19,"title":["Actinomycosis of the middle ear"],"prefix":"10.1017","volume":"127","author":[{"given":"PJ","family":"Kullar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Yates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2013,6,13]]},"reference":[{"key":"S0022215113001230_ref19","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-195606000-00014"},{"key":"S0022215113001230_ref21","first-page":"29","article-title":"Actinomycosis of the middle ear: case report [in French]","volume":"126","author":"Oudidi","year":"2005","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"S0022215113001230_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31802c74ae"},{"key":"S0022215113001230_ref4","doi-asserted-by":"publisher","DOI":"10.1086\/516337"},{"key":"S0022215113001230_ref5","doi-asserted-by":"publisher","DOI":"10.2165\/00066982-200106040-00012"},{"key":"S0022215113001230_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(89)90293-0"},{"key":"S0022215113001230_ref25","first-page":"65","article-title":"Actinomycosis of the middle ear [in German]","volume":"32","author":"Gattaz","year":"1984","journal-title":"HNO"},{"key":"S0022215113001230_ref8","doi-asserted-by":"publisher","DOI":"10.1177\/000348941011900507"},{"key":"S0022215113001230_ref18","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197402000-00011"},{"key":"S0022215113001230_ref1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d6099"},{"key":"S0022215113001230_ref20","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100045758"},{"key":"S0022215113001230_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31818c3223"},{"key":"S0022215113001230_ref22","first-page":"369","article-title":"Actinomycosis of the middle ear [in Polish]","volume":"56","author":"Skladzien","year":"2002","journal-title":"Otolaryngol Pol"},{"key":"S0022215113001230_ref14","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1993.01880170087018"},{"key":"S0022215113001230_ref30","first-page":"94","article-title":"Actinomycosis of the middle ear and mastoid process [in Russian]","volume":"20","author":"Kulina","year":"1958","journal-title":"Vestn Otorinolaringol"},{"key":"S0022215113001230_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100139362"},{"key":"S0022215113001230_ref2","first-page":"105","article-title":"James Israel (1848\u20131926). 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