{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T01:24:34Z","timestamp":1766625874755},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2013,6,11]],"date-time":"2013-06-11T00:00:00Z","timestamp":1370908800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S002221511300131X_sec1\"><jats:title>Background:<\/jats:title><jats:p>The management of frontal sinus disease in cystic fibrosis patients represents a challenge for many surgeons. Procedures can vary from the minimally invasive to those involving extensive open surgery.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511300131X_sec2\"><jats:title>Objective:<\/jats:title><jats:p>This study describes the outcomes of the endoscopic modified Lothrop procedure, in terms of safety and morbidity, for cystic fibrosis patients with frontal sinus disease who did not improve following traditional functional endoscopic sinus surgery.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511300131X_sec3\"><jats:title>Method and results:<\/jats:title><jats:p>The study setting was a tertiary referral unit in a London teaching hospital, the largest national base for adult cystic fibrosis patients. Two patients diagnosed in childhood with cystic fibrosis presented with histories of recurrent, severe frontal sinusitis; both had previously undergone multiple endoscopic sinus surgical procedures. The modified Lothrop procedure was performed on both patients. The outcome measures were symptom resolution and post-operative complications.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511300131X_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>The endoscopic modified Lothrop procedure was beneficial in the cystic fibrosis patients with frontal sinus disease who failed to respond to standard functional endoscopic sinus surgery procedures.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s002221511300131x","type":"journal-article","created":{"date-parts":[[2013,6,11]],"date-time":"2013-06-11T06:27:11Z","timestamp":1370932031000},"page":"666-669","source":"Crossref","is-referenced-by-count":8,"title":["Modified Lothrop procedure in cystic fibrosis patients: does it have a role?"],"prefix":"10.1017","volume":"127","author":[{"given":"M-C","family":"Jaberoo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M-A","family":"Pulido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H A","family":"Saleh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,6,11]]},"reference":[{"key":"S002221511300131X_ref10","doi-asserted-by":"publisher","DOI":"10.2500\/105065897781446784"},{"key":"S002221511300131X_ref12","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.111593"},{"key":"S002221511300131X_ref18","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890230055011"},{"key":"S002221511300131X_ref13","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00043305"},{"key":"S002221511300131X_ref17","first-page":"1207","article-title":"Cystic fibrosis patients who have undergone heart-lung transplantation benefit from maxillary sinus antrostomy and repeated sinus lavage","volume":"23","author":"Lewiston","year":"1991","journal-title":"Transplant Proc"},{"key":"S002221511300131X_ref11","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.162"},{"key":"S002221511300131X_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-1993(09)60005-9"},{"key":"S002221511300131X_ref14","doi-asserted-by":"publisher","DOI":"10.1136\/thx.47.6.426"},{"key":"S002221511300131X_ref1","doi-asserted-by":"publisher","DOI":"10.1002\/1099-0496(200012)30:6<481::AID-PPUL8>3.0.CO;2-N"},{"key":"S002221511300131X_ref16","doi-asserted-by":"publisher","DOI":"10.1136\/thx.52.4.318"},{"key":"S002221511300131X_ref15","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199504000-00002"},{"key":"S002221511300131X_ref19","doi-asserted-by":"publisher","DOI":"10.1177\/019459988709700403"},{"key":"S002221511300131X_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(92)90183-3"},{"key":"S002221511300131X_ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199812000-00009"},{"key":"S002221511300131X_ref2","doi-asserted-by":"publisher","DOI":"10.1080\/028418501127347214"},{"key":"S002221511300131X_ref20","doi-asserted-by":"publisher","DOI":"10.2500\/105065897781446810"},{"key":"S002221511300131X_ref7","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199612000-00019"},{"key":"S002221511300131X_ref21","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1177\/194589240401800310","article-title":"The effect of the modified endoscopic Lothrop procedure on the mucociliary clearance of the frontal sinus in an animal model","volume":"18","author":"Rajapaksa","year":"2004","journal-title":"Am J Rhinol"},{"key":"S002221511300131X_ref5","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.112870"},{"key":"S002221511300131X_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-1810(10)80090-9"},{"key":"S002221511300131X_ref4","unstructured":"Cystic Fibrosis Foundation. Patient Registry 2004. Annual Data Report. 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