{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T03:02:27Z","timestamp":1649214147397},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T00:00:00Z","timestamp":1397520000000},"content-version":"unspecified","delay-in-days":14,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215114000681_sec1\"><jats:title>Objective:<\/jats:title><jats:p>We aimed to identify the role of major respiratory viruses in the aetiology of human nasal polyps using polymerase chain reaction technique.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114000681_sec2\"><jats:title>Methods:<\/jats:title><jats:p>Thirty patients with nasal polyps and a group of 20 healthy patients (control group) were included in this study. Mucosa was obtained from the polyps of patients with nasal polyposis and from the middle turbinate of the control group patients by means of biopsy. The samples were stored at \u221280\u00a0\u00b0C until molecular analysis by polymerase chain reaction was carried out.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114000681_sec3\"><jats:title>Results:<\/jats:title><jats:p>In the control group, the human coronavirus and human rhinovirus were diagnosed in one of the patients and the human respiratory syncytial virus in another. In the group with nasal polyposis, the influenza B virus was identified in one of the patients and the human coronavirus in another.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114000681_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>The results did not demonstrate a statistically significant relationship between nasal polyposis and respiratory viruses.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215114000681","type":"journal-article","created":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T09:13:50Z","timestamp":1397553230000},"page":"356-359","source":"Crossref","is-referenced-by-count":0,"title":["Investigation of the role of major respiratory viruses in the aetiology of nasal polyps using polymerase chain reaction technique"],"prefix":"10.1017","volume":"128","author":[{"given":"F","family":"Aksoy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Yenigun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Dogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O","family":"Ozturan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V B","family":"Yenigun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,4,15]]},"reference":[{"key":"S0022215114000681_ref19","first-page":"F55","article-title":"Papillomavirus infections \u2013 a major cause of human cancers","volume":"1288","author":"Zur Hausen","year":"1996","journal-title":"Biochim Biophys Acta"},{"key":"S0022215114000681_ref18","first-page":"344","article-title":"Search for the human papillomavirus in nasal polyps, using a polymerase chain reaction-method","volume":"23","author":"Becker","year":"1994","journal-title":"J Otolaryngol"},{"key":"S0022215114000681_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21534"},{"key":"S0022215114000681_ref14","first-page":"1111","article-title":"Detection of Epstein\u2013Barr virus-infected mucosal lymphocytes in nasal polyps","volume":"149","author":"Tao","year":"1996","journal-title":"Am J Pathol"},{"key":"S0022215114000681_ref13","doi-asserted-by":"publisher","DOI":"10.2500\/108854196778662246"},{"key":"S0022215114000681_ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200404000-00022"},{"key":"S0022215114000681_ref6","first-page":"57","volume-title":"Diseases of the Sinuses: Diagnoses and Management","author":"Tos","year":"2001"},{"key":"S0022215114000681_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2008.01.046"},{"key":"S0022215114000681_ref17","first-page":"15","article-title":"Prevalence of human papillomaviruses (HPV) in benign and malignant tumors of the upper respiratory tract","volume":"9","author":"Shen","year":"1996","journal-title":"Mod Pathol"},{"key":"S0022215114000681_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2005.07.019"},{"key":"S0022215114000681_ref5","first-page":"549","article-title":"Further experiments in the viral theory of nasal polyp etiology","volume":"24","author":"Weille","year":"1966","journal-title":"Ann Allergy"},{"key":"S0022215114000681_ref15","first-page":"404","article-title":"Nasal polyposis: in search of a viral etiology using DNA hybridization","volume":"20","author":"Kozak","year":"1991","journal-title":"J Otolaryngol"},{"key":"S0022215114000681_ref8","first-page":"1051","article-title":"Mutations and differential expression of the ras family genes in human nasal polyposis","volume":"31","author":"Zaravinos","year":"2007","journal-title":"Int J Oncol"},{"key":"S0022215114000681_ref3","doi-asserted-by":"publisher","DOI":"10.1258\/002221503321046577"},{"key":"S0022215114000681_ref7","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1177\/194589240401800502","article-title":"Transforming growth factor beta1 in nasal remodeling: differences between chronic rhinosinusitis and nasal polyposis","volume":"18","author":"Watelet","year":"2004","journal-title":"Am J Rhinol"},{"key":"S0022215114000681_ref1","first-page":"7","volume-title":"Nasal Polyps: Epidemiology, Pathogenesis and Treatment","author":"Brain","year":"1997"},{"key":"S0022215114000681_ref2","first-page":"49","article-title":"Flunisolide nasal spray 0.025% in the prophylactic treatment of nasal polyposis after polypectomy. 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