{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T19:10:46Z","timestamp":1781809846719,"version":"3.54.5"},"reference-count":27,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2014,6,23]],"date-time":"2014-06-23T00:00:00Z","timestamp":1403481600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215114001066_sec1\"><jats:title>Objective:<\/jats:title><jats:p>We wanted to identify the presentation, diagnostic work-up and treatment outcomes of patients with sinonasal malignancy at Derriford Hospital, Plymouth, UK and compare these with the European Position Paper on Endoscopic Management of Tumours of the Nose, Paranasal Sinuses and Skull Base.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114001066_sec2\"><jats:title>Materials and methods:<\/jats:title><jats:p>This was a retrospective audit of all patients diagnosed with sinonasal malignancy over a five-year period. The clinical records and picture archiving and communications system data of the patients were reviewed.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114001066_sec3\"><jats:title>Results:<\/jats:title><jats:p>Thirty patients with sinonasal malignancy were identified out of 570 head and neck cancer patients. The nasal cavity was the most common site for presentation, followed by the maxillary sinuses. Fifty per cent of patients had a squamous cell carcinoma and 27 per cent had a malignant melanoma. Half of the patients presented at stage IV of the cancer and 20 per cent at stage III. Thirty-seven per cent of patients underwent surgical management and only 20 per cent of the total patient group underwent endoscopic surgery. The mortality in our series was 30 per cent over the studied period.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114001066_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>Late-stage presentation of sinonasal malignancy has resulted in increased patient mortality in our case series. Also, we found a high incidence of malignant melanoma with high recurrence and survival rates.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215114001066","type":"journal-article","created":{"date-parts":[[2014,6,24]],"date-time":"2014-06-24T11:10:05Z","timestamp":1403608205000},"page":"654-657","source":"Crossref","is-referenced-by-count":39,"title":["Sinonasal malignancy: presentation and outcomes"],"prefix":"10.1017","volume":"128","author":[{"given":"Y B","family":"Mahalingappa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H S","family":"Khalil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2014,6,23]]},"reference":[{"key":"S0022215114001066_ref21","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000339121.20101.85"},{"key":"S0022215114001066_ref19","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2005.19.1.7"},{"key":"S0022215114001066_ref12","first-page":"246","article-title":"Malignant neoplasms of the nasal cavity and paranasal sinuses. 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