{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:32:11Z","timestamp":1760985131295},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2014,7,8]],"date-time":"2014-07-08T00:00:00Z","timestamp":1404777600000},"content-version":"unspecified","delay-in-days":7,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215114001418_sec1\"><jats:title>Objective:<\/jats:title><jats:p>To determine the value of non echo planar, diffusion-weighted magnetic resonance imaging for detection of residual and recurrent middle-ear cholesteatoma after combined-approach tympanoplasty.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114001418_sec2\"><jats:title>Method:<\/jats:title><jats:p>The magnetic resonance imaging findings after primary surgery for cholesteatoma were compared with intra-operative findings at \u2018second-look\u2019 surgery or with clinical follow-up findings.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114001418_sec3\"><jats:title>Results:<\/jats:title><jats:p>Forty-eight magnetic resonance imaging studies were performed in 38 patients. Second-look surgery was performed 21 times in 18 patients. The remaining patients were followed up at the out-patient clinic. There were no false-positive findings with non echo planar, diffusion-weighted magnetic resonance imaging; however, there were four false-negative findings. The mean maximum diameter of recurrent cholesteatoma, as assessed using magnetic resonance imaging, was 11.7\u00a0mm (range, 4.4\u201325.3\u00a0mm). The sensitivity of non echo planar, diffusion-weighted magnetic resonance imaging for detecting cholesteatoma prior to second-look surgery was 0.76, with a specificity of 1.00. When clinical follow up of the non-operated ears was included in the analysis, sensitivity was 0.81 and specificity was 1.00.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114001418_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>Recurrent cholesteatoma can be accurately detected using non echo planar, diffusion-weighted magnetic resonance imaging. Our study, however, also showed some false-negative results. Therefore, strict out-patient follow up is mandatory for those considering using this technique instead of standard second-look surgery.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215114001418","type":"journal-article","created":{"date-parts":[[2014,7,8]],"date-time":"2014-07-08T13:14:04Z","timestamp":1404825244000},"page":"599-603","source":"Crossref","is-referenced-by-count":18,"title":["The value of non echo planar, diffusion-weighted magnetic resonance imaging for the detection of residual or recurrent middle-ear cholesteatoma"],"prefix":"10.1017","volume":"128","author":[{"given":"S","family":"Velthuis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K J","family":"van Everdingen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J J","family":"Quak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D R","family":"Colnot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,7,8]]},"reference":[{"key":"S0022215114001418_ref14","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215110002197"},{"key":"S0022215114001418_ref11","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2824"},{"key":"S0022215114001418_ref13","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31815dbae8"},{"key":"S0022215114001418_ref9","first-page":"1480","article-title":"Single-shot, turbo spin-echo, diffusion-weighted imaging versus spin-echo-planar, diffusion-weighted imaging in the detection of acquired middle ear cholesteatoma","volume":"27","author":"De Foer","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"S0022215114001418_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-007-0268-3"},{"key":"S0022215114001418_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215112000679"},{"key":"S0022215114001418_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31822e938d"},{"key":"S0022215114001418_ref1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.1999.00238.x"},{"key":"S0022215114001418_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2010.03.023"},{"key":"S0022215114001418_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.10118"},{"key":"S0022215114001418_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-006-0160-2"},{"key":"S0022215114001418_ref10","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2381041649"},{"key":"S0022215114001418_ref2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.176.2.2367654"},{"key":"S0022215114001418_ref12","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31818edf4a"},{"key":"S0022215114001418_ref6","first-page":"847","article-title":"Diffusion-weighted imaging for differentiating recurrent cholesteatoma from granulation tissue after mastoidectomy: case report","volume":"23","author":"Maheshwari","year":"2002","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215114001418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T03:05:59Z","timestamp":1555902359000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215114001418\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0022215114001418"],"URL":"https:\/\/doi.org\/10.1017\/s0022215114001418","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}