{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T18:58:02Z","timestamp":1778007482963,"version":"3.51.4"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2014,7,7]],"date-time":"2014-07-07T00:00:00Z","timestamp":1404691200000},"content-version":"unspecified","delay-in-days":6,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S002221511400142X_sec1\"><jats:title>Objectives:<\/jats:title><jats:p>This study aimed to evaluate the demographics of spasmodic dysphonia in the Indian population and to analyse the optimum dose titration of botulinum toxin type A in this group. A comparative analysis with international studies was also performed.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511400142X_sec2\"><jats:title>Method:<\/jats:title><jats:p>The study involved a retrospective analysis and audit of botulinum toxin type A dose titration in spasmodic dysphonia patients who visited our voice clinic between January 2005 and January 2012.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511400142X_sec3\"><jats:title>Results:<\/jats:title><jats:p>The average total therapeutic dose required for patients with adductor spasmodic dysphonia was 4.2 U per patient per vocal fold (total 8.4 U per patient), and for patients with abductor spasmodic dysphonia, it was 4.6 U per patient.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511400142X_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>Our audit revealed that 80 per cent of the spasmodic dysphonia patients were male, which contrasts dramatically with international studies, wherein around 80 per cent of spasmodic dysphonia patients were female. Our study also revealed a higher dose titration of botulinum toxin for the Indian spasmodic dysphonia population in both adductor and abductor spasmodic dysphonia cases.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s002221511400142x","type":"journal-article","created":{"date-parts":[[2014,7,7]],"date-time":"2014-07-07T12:45:31Z","timestamp":1404737131000},"page":"649-653","source":"Crossref","is-referenced-by-count":8,"title":["Spasmodic dysphonia: a seven-year audit of dose titration and demographics in the Indian population"],"prefix":"10.1017","volume":"128","author":[{"given":"N K","family":"Nerurkar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T P","family":"Banu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,7,7]]},"reference":[{"key":"S002221511400142X_ref15","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813484685"},{"key":"S002221511400142X_ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200102000-00006"},{"key":"S002221511400142X_ref12","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000201"},{"key":"S002221511400142X_ref11","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/108.2.463"},{"key":"S002221511400142X_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhq023"},{"key":"S002221511400142X_ref3","doi-asserted-by":"publisher","DOI":"10.1044\/1058-0360(2003\/087)"},{"key":"S002221511400142X_ref2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.63.5.688"},{"key":"S002221511400142X_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199810000-00003"},{"key":"S002221511400142X_ref5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.5005\/jp-journals-10023-1010","article-title":"Flaring of ala nasi: a reliable diagnostic sign for abductor spasmodic dysphonia","volume":"1","author":"Menon","year":"2011","journal-title":"International Journal of Phonosurgery and Laryngology"},{"key":"S002221511400142X_ref14","volume-title":"The Use of Botulinum Toxin in Otolaryngology: A Practical Guide","author":"Pou","year":"2005"},{"key":"S002221511400142X_ref7","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1288\/00005537-199108000-00019","article-title":"A method for the treatment of abductor spasmodic dysphonia with botulinum toxin injections: a preliminary report","volume":"101","author":"Rontal","year":"1991","journal-title":"Laryngoscope"},{"key":"S002221511400142X_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(05)80168-7"},{"key":"S002221511400142X_ref9","doi-asserted-by":"publisher","DOI":"10.1177\/000348940411300802"},{"key":"S002221511400142X_ref6","first-page":"403","article-title":"Electromyographic assessment of spasmodic dysphonia patients prior to botulinum toxin injection","volume":"34","author":"Rodriquez","year":"1994","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"S002221511400142X_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9924(81)90037-X"},{"key":"S002221511400142X_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.10.033"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221511400142X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T05:46:27Z","timestamp":1716961587000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221511400142X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S002221511400142X"],"URL":"https:\/\/doi.org\/10.1017\/s002221511400142x","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}