{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T05:13:27Z","timestamp":1769577207914,"version":"3.49.0"},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2014,10,2]],"date-time":"2014-10-02T00:00:00Z","timestamp":1412208000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215114002175_sec1\"><jats:title>Background:<\/jats:title><jats:p>Patients with laryngectomy tracheostomas are at risk of developing acute airway obstruction due to mucous crusting. Current management relies on saline nebulisers, followed by suction and manual evacuation to remove the obstruction. This paper describes the first reported case of using N-acetylcysteine nebulisers in addition to saline to adequately soften the mucous plugs in order to facilitate removal.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114002175_sec2\"><jats:title>Case report:<\/jats:title><jats:p>A 68-year-old female attended the emergency department with a partial obstruction of her laryngectomy tracheostoma as a result of mucous crusting. Saline nebulisers did not provide adequate softening to allow the obstructing mucous plugs to be removed. N-acetylcysteine nebulisers were used to further soften the mucous plugs which successfully resulted in their removal.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215114002175_sec3\"><jats:title>Conclusion:<\/jats:title><jats:p>N-acetylcysteine nebulisers can be used to assist in the removal of mucous plugs in saline-resistant cases.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215114002175","type":"journal-article","created":{"date-parts":[[2014,10,2]],"date-time":"2014-10-02T10:47:32Z","timestamp":1412246852000},"page":"1123-1124","source":"Crossref","is-referenced-by-count":3,"title":["Nebulised N-acetylcysteine used in acute tracheostoma obstruction"],"prefix":"10.1017","volume":"128","author":[{"given":"A","family":"Patel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Theokli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,10,2]]},"reference":[{"key":"S0022215114002175_ref2","first-page":"534","article-title":"Long-term care of the patient with a tracheostomy","volume":"50","author":"Lewarski","year":"2005","journal-title":"Respir Care"},{"key":"S0022215114002175_ref1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100117852"},{"key":"S0022215114002175_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2013.04.016"},{"key":"S0022215114002175_ref6","first-page":"513","article-title":"Acetylcholine: a drug that is much more than a mucokinetic","volume":"42","author":"Zimet","year":"1988","journal-title":"Biomed Pharmacother"},{"key":"S0022215114002175_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20974"},{"key":"S0022215114002175_ref5","first-page":"467","article-title":"N-acetylcysteine","volume":"5","year":"2000","journal-title":"Altern Med Rev"},{"key":"S0022215114002175_ref7","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007168.pub2"},{"key":"S0022215114002175_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0007-0971(85)90046-4"},{"key":"S0022215114002175_ref9","doi-asserted-by":"publisher","DOI":"10.1136\/thx.40.11.832"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215114002175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T21:23:32Z","timestamp":1555881812000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215114002175\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,2]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["S0022215114002175"],"URL":"https:\/\/doi.org\/10.1017\/s0022215114002175","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,2]]}}}