{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:17:02Z","timestamp":1792275422716,"version":"4.4.0"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T00:00:00Z","timestamp":1419206400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S002221511400293X_sec1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Rhabdomyosarcoma is a malignant mesenchymal neoplasm rarely diagnosed in the larynx. Traditionally, it has been treated by radical surgery (i.e. total laryngectomy), followed by radiation and\/or chemotherapy. Recent advances suggest that it may be treated with combination therapy comprising high-dose radiation and pulse chemotherapy, with a high success rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S002221511400293X_sec2\">\n                    <jats:title>Case report:<\/jats:title>\n                    <jats:p>We report the first documented case of subglottic embryonal rhabdomyosarcoma in an adolescent female treated with chemoradiation alone, and review the literature reflecting a move towards organ preservation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S002221511400293X_sec3\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>While surgery has been successfully used to treat this neoplasm, combination therapy, as described in our study, also seems effective and has the added advantage of preserving laryngeal function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s002221511400293x","type":"journal-article","created":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T06:30:43Z","timestamp":1419229843000},"page":"106-109","source":"Crossref","is-referenced-by-count":14,"title":["A rare case of subglottic embryonal rhabdomyosarcoma: managed with the aim of organ preservation"],"prefix":"10.1017","volume":"129","author":[{"given":"A","family":"Jain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S N","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Singhal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M P","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2014,12,22]]},"reference":[{"key":"S002221511400293X_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(65)90043-7"},{"key":"S002221511400293X_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950110413"},{"key":"S002221511400293X_ref2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100141416"},{"key":"S002221511400293X_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870301)59:5<1012::AID-CNCR2820590527>3.0.CO;2-A"},{"key":"S002221511400293X_ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.130.10.1217"},{"key":"S002221511400293X_ref7","first-page":"89","article-title":"Embryonal rhabdomyosarcoma of the larynx in a child: Report of a case and review of literature","volume":"25","author":"Fernandes","year":"1988","journal-title":"Indian J Cancer"},{"key":"S002221511400293X_ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1961.00740030210015"},{"key":"S002221511400293X_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(80)80028-7"},{"key":"S002221511400293X_ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1991.01870220133025"},{"key":"S002221511400293X_ref10","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198402000-00010"},{"key":"S002221511400293X_ref15","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1007\/s003300050544","article-title":"Laryngeal embryonal rhabdomyosarcoma in a child: MRI appearance","volume":"8","author":"Mortele","year":"1998","journal-title":"Eur Radiol"},{"key":"S002221511400293X_ref8","doi-asserted-by":"publisher","DOI":"10.1177\/000348948309200120"},{"key":"S002221511400293X_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(01)00105-1"},{"key":"S002221511400293X_ref14","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950190208"},{"key":"S002221511400293X_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(88)90055-9"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221511400293X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T15:45:25Z","timestamp":1555861525000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221511400293X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,22]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S002221511400293X"],"URL":"https:\/\/doi.org\/10.1017\/s002221511400293x","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,22]]}}}