{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T05:23:54Z","timestamp":1768281834741,"version":"3.49.0"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T00:00:00Z","timestamp":1424044800000},"content-version":"unspecified","delay-in-days":15,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215115000067_sec1\"><jats:title>Background:<\/jats:title><jats:p>Branchial cleft cysts occur because of a failure of involution of the second branchial cleft. However, as well-differentiated squamous cell carcinoma can mimic branchial cleft cysts, there is a lack of consensus on the appropriate management of cystic neck lumps.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115000067_sec2\"><jats:title>Objective:<\/jats:title><jats:p>To report our experience of fine needle aspiration cytology and frozen section examination in the management of cystic neck lumps.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115000067_sec3\"><jats:title>Method:<\/jats:title><jats:p>Retrospective case note review of patients managed in the Southern General Hospital, Scotland, UK.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115000067_sec4\"><jats:title>Results:<\/jats:title><jats:p>The sensitivity of fine needle aspiration cytology and frozen section for detecting branchial cleft cysts was 75 per cent and 100 per cent respectively. Two patients who did not undergo intra-operative frozen section examination were either over- or under-treated, which is discussed.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115000067_sec5\"><jats:title>Conclusion:<\/jats:title><jats:p>Adult patients subjected to surgical excision of a suspected branchial cyst should undergo intra-operative frozen section analysis regardless of clinical suspicion for malignancy. This part of management is critical to ensure patients are offered appropriate treatment.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215115000067","type":"journal-article","created":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T07:31:10Z","timestamp":1424071870000},"page":"174-178","source":"Crossref","is-referenced-by-count":20,"title":["Fine needle aspiration cytology versus frozen section in branchial cleft cysts"],"prefix":"10.1017","volume":"129","author":[{"given":"F","family":"Begbie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Visvanathan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L J","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,2,16]]},"reference":[{"key":"S0022215115000067_ref7","doi-asserted-by":"publisher","DOI":"10.3109\/00016480903127450"},{"key":"S0022215115000067_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-008-9786-3"},{"key":"S0022215115000067_ref8","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198201000-00006"},{"key":"S0022215115000067_ref6","doi-asserted-by":"publisher","DOI":"10.1503\/cjs.011112"},{"key":"S0022215115000067_ref2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880528"},{"key":"S0022215115000067_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0503(79)80009-0"},{"key":"S0022215115000067_ref20","unstructured":"National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Head and Neck Cancers. In: http:\/\/www.nccn.org\/professionals\/physician_gls\/f_guidelines.asp [20 December 2014]"},{"key":"S0022215115000067_ref5","doi-asserted-by":"crossref","first-page":"242","DOI":"10.47102\/annals-acadmedsg.V35N4p242","article-title":"Accuracy of fine needle aspiration cytology and frozen section histopathology for lesions of the major salivary glands","volume":"35","author":"Tan","year":"2006","journal-title":"Ann Acad Med Singapore"},{"key":"S0022215115000067_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2005.02.017"},{"key":"S0022215115000067_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20796"},{"key":"S0022215115000067_ref1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2003.0020"},{"key":"S0022215115000067_ref15","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000147950.35923.ba"},{"key":"S0022215115000067_ref3","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.50.12.1005"},{"key":"S0022215115000067_ref18","doi-asserted-by":"publisher","DOI":"10.5858\/2008-132-29-IFDCRT"},{"key":"S0022215115000067_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199804000-00006"},{"key":"S0022215115000067_ref13","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.128600"},{"key":"S0022215115000067_ref17","first-page":"393","article-title":"Quality assessment of intraoperative frozen sections in a teaching hospital: an analysis of 847 consecutive cases [in French]","volume":"23","author":"Wendum","year":"2003","journal-title":"Ann Pathol"},{"key":"S0022215115000067_ref19","volume-title":"Guidance on Cancer Services \u2013 Improving Outcomes in Head and Neck Cancers \u2013 The Manual","year":"2004"},{"key":"S0022215115000067_ref10","first-page":"867","article-title":"The case for branchiogenic cancer (malignant branchioma)","volume":"32","author":"Martin","year":"1950","journal-title":"Ann Surg"},{"key":"S0022215115000067_ref21","doi-asserted-by":"publisher","DOI":"10.1258\/00222150360600977"},{"key":"S0022215115000067_ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200304000-00011"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215115000067","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T20:48:08Z","timestamp":1691268488000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215115000067\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S0022215115000067"],"URL":"https:\/\/doi.org\/10.1017\/s0022215115000067","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2]]}}}