{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T09:52:55Z","timestamp":1784281975333,"version":"3.55.0"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2015,3,19]],"date-time":"2015-03-19T00:00:00Z","timestamp":1426723200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S002221511500064X_sec1\"><jats:title>Background:<\/jats:title><jats:p>A large proportion of patients with vocal fold polyps are cigarette smokers. However, prior to this report no comparative study of polyp histopathology in smokers versus non-smokers had been performed.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511500064X_sec2\"><jats:title>Methods:<\/jats:title><jats:p>A prospective histopathological study of vocal fold polyps excised from 29 patients was undertaken. This comprised a comparative analysis of polyp histopathology in smokers versus non-smokers and a review of the pertinent literature.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511500064X_sec3\"><jats:title>Results:<\/jats:title><jats:p>Vocal fold polyps were larger in smokers than in non-smokers. Histopathological features significantly associated with the polyps of smokers versus those of non-smokers were increased keratinisation, dysplasia, a basement membrane thinning and hyaline degeneration.<\/jats:p><\/jats:sec><jats:sec id=\"S002221511500064X_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>Cigarette smoke has an injurious effect on vocal fold polyp epithelium and leads to increased hyaline degeneration in polyps.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s002221511500064x","type":"journal-article","created":{"date-parts":[[2015,3,19]],"date-time":"2015-03-19T09:58:14Z","timestamp":1426759094000},"page":"484-488","source":"Crossref","is-referenced-by-count":14,"title":["A comparative histopathological study of vocal fold polyps in smokers versus non-smokers"],"prefix":"10.1017","volume":"129","author":[{"given":"K G","family":"Effat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Milad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,3,19]]},"reference":[{"key":"S002221511500064X_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2003.07.003"},{"key":"S002221511500064X_ref18","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200312000-00009"},{"key":"S002221511500064X_ref17","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000184505.05662.b9"},{"key":"S002221511500064X_ref15","doi-asserted-by":"publisher","DOI":"10.1177\/000348949610500706"},{"key":"S002221511500064X_ref12","doi-asserted-by":"publisher","DOI":"10.1177\/000348940811700114"},{"key":"S002221511500064X_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0863-x"},{"key":"S002221511500064X_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22226"},{"key":"S002221511500064X_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2003.11.007"},{"key":"S002221511500064X_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100091167"},{"key":"S002221511500064X_ref2","doi-asserted-by":"publisher","DOI":"10.1177\/000348948209100410"},{"key":"S002221511500064X_ref1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22421"},{"key":"S002221511500064X_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-011-0342-3"},{"key":"S002221511500064X_ref14","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111000216"},{"key":"S002221511500064X_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2009.05.002"},{"key":"S002221511500064X_ref11","doi-asserted-by":"crossref","first-page":"3523","DOI":"10.3760\/cma.j.issn.0366-6999.20131206","article-title":"Clinical classification and treatment of leukokeratosis of the vocal cords","volume":"126","author":"Li-jing","year":"2013","journal-title":"Chin Med J"},{"key":"S002221511500064X_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2007.05.011"},{"key":"S002221511500064X_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215105005360"},{"key":"S002221511500064X_ref20","doi-asserted-by":"publisher","DOI":"10.1177\/000348949810700711"},{"key":"S002221511500064X_ref24","first-page":"59","volume-title":"General Pathology","author":"Walter","year":"1979"},{"key":"S002221511500064X_ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199910000-00025"},{"key":"S002221511500064X_ref21","doi-asserted-by":"publisher","DOI":"10.1121\/1.1648974"},{"key":"S002221511500064X_ref16","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318174e09b"},{"key":"S002221511500064X_ref23","doi-asserted-by":"publisher","DOI":"10.1177\/1066896911411480"},{"key":"S002221511500064X_ref7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2000.00352.x"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221511500064X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T22:49:35Z","timestamp":1717800575000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221511500064X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,19]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S002221511500064X"],"URL":"https:\/\/doi.org\/10.1017\/s002221511500064x","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,19]]}}}