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This review discusses some suggested revisions on tumour\u2013node\u2013metastasis staging of human papillomavirus negative upper aerodigestive tract cancers.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115002686_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>The seventh edition of<jats:italic>The American Joint Committee on Cancer Staging Manual<\/jats:italic>was reviewed and important issues that could be considered for revision were identified and discussed.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115002686_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>According to our assessment of the oncological outcomes of previous studies, the following factors should be considered for revision: anterior commissure involvement and subglottic extension in laryngeal cancers; underlying bone involvement in hard palate and upper alveolar ridge cancers; tumour thickness in oral cancers; and extracapsular spread and carotid artery involvement in neck metastases.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115002686_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Sufficient data on the prognostic importance of these issues have been reported. 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