{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T22:50:25Z","timestamp":1792450225961,"version":"4.5.0"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2015,12,17]],"date-time":"2015-12-17T00:00:00Z","timestamp":1450310400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215115003333_sec_a1\"><jats:title>Background:<\/jats:title><jats:p>Giant basal cell carcinoma, in which the tumour measures 5 cm or greater in diameter, is a very rare skin malignancy that accounts for less than 1 per cent of all basal cell tumours. Very few studies have reported on the incidence, resection and reconstruction of this lesion worldwide.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115003333_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>In total, 17 patients with giant basal cell carcinoma of the head and neck region underwent surgical excision and reconstruction at our hospital. Medical charts were retrospectively reviewed and analysed.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115003333_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>The lesion was usually in the forehead, eyelid, lips or nasal-cheek region. The greatest diameter ranged from 5 to 11 cm, with 5\u20136 cm being the most common size at the time of presentation. All patients had their tumour resected and reconstructed in a single-stage procedure, mostly with a local advancement flap, and with no post-operative flap failure.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215115003333_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Giant basal cell carcinoma of the head and neck can be successfully treated with a local flap in a single-stage approach.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215115003333","type":"journal-article","created":{"date-parts":[[2015,12,17]],"date-time":"2015-12-17T08:57:08Z","timestamp":1450342628000},"page":"176-182","source":"Crossref","is-referenced-by-count":9,"title":["Giant basal cell carcinoma of the face: surgical management and challenges for reconstruction"],"prefix":"10.1017","volume":"130","author":[{"given":"A","family":"Maimaiti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Mijiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Yarbag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Moming","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,12,17]]},"reference":[{"key":"S0022215115003333_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1986.tb01993.x"},{"key":"S0022215115003333_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1226(50)80042-5"},{"key":"S0022215115003333_ref6","volume-title":"AJCC Cancer Staging Manual","author":"Page","year":"2002"},{"key":"S0022215115003333_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70098-2"},{"key":"S0022215115003333_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04165.x"},{"key":"S0022215115003333_ref19","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1983.01650290013008"},{"key":"S0022215115003333_ref12","first-page":"2655","article-title":"Giant basal cell carcinoma: clinicopathological analysis of 51 cases and review of the literature","volume":"29","author":"Archontaki","year":"2009","journal-title":"Anticancer Res"},{"key":"S0022215115003333_ref7","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19940115)73:2<328::AID-CNCR2820730216>3.0.CO;2-U"},{"key":"S0022215115003333_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31822b67e3"},{"key":"S0022215115003333_ref17","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199105000-00014"},{"key":"S0022215115003333_ref20","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200009010-00021"},{"key":"S0022215115003333_ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198005000-00017"},{"key":"S0022215115003333_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2009.09.004"},{"key":"S0022215115003333_ref5","first-page":"77","article-title":"Treatment of basal cell carcinoma: a review [in Chinese]","volume":"9","author":"Ding","year":"2011","journal-title":"Oncol Prog"},{"key":"S0022215115003333_ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.155"},{"key":"S0022215115003333_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04427.x"},{"key":"S0022215115003333_ref13","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930901)72:5<1624::AID-CNCR2820720522>3.0.CO;2-D"},{"key":"S0022215115003333_ref15","first-page":"10","volume-title":"World Health Organization Classification of Tumors. 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