{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:00:05Z","timestamp":1787061605521,"version":"build-2736575974"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T00:00:00Z","timestamp":1454544000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215116000207_sec_a1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate nasal mucociliary clearance in patients with Beh\u00e7et's disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215116000207_sec_a2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Thirty patients with Beh\u00e7et's disease, diagnosed on the basis of criteria defined by the International Study Group for Beh\u00e7et's Disease, and 30 healthy individuals were recruited. In both groups, individuals with conditions that could affect nasal mucociliary clearance were excluded. Nasal mucociliary clearance time was evaluated using saccharin tests. The time between placement of a saccharin tablet and the tasting of the saccharin was measured and recorded as the saccharin clearance time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215116000207_sec_a3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean nasal mucociliary clearance time was significantly longer in the Beh\u00e7et's disease patients than in the control subjects (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). Furthermore, there was a positive correlation between Beh\u00e7et's disease duration and nasal mucociliary clearance time (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001, r = 0.882).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215116000207_sec_a4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The results suggest that nasal mucociliary clearance time is longer in Beh\u00e7et's disease patients than in control subjects, and is positively correlated with disease duration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215116000207","type":"journal-article","created":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T04:33:15Z","timestamp":1454560395000},"page":"348-351","source":"Crossref","is-referenced-by-count":12,"title":["Assessment of nasal mucociliary activity in patients with Beh\u00e7et's disease"],"prefix":"10.1017","volume":"130","author":[{"given":"I","family":"Ozbay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Kucur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Tem\u0130zturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Ozkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Kahraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Oghan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"S0022215116000207_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2013.07.014"},{"key":"S0022215116000207_ref15","doi-asserted-by":"publisher","DOI":"10.3109\/00016488309132888"},{"key":"S0022215116000207_ref9","first-page":"1078","article-title":"Criteria for diagnosis of Beh\u00e7et's disease","volume":"335","year":"1990","journal-title":"Lancet"},{"key":"S0022215116000207_ref18","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-200002000-00010"},{"key":"S0022215116000207_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200001000-00021"},{"key":"S0022215116000207_ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-009-1116-3"},{"key":"S0022215116000207_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000001202"},{"key":"S0022215116000207_ref6","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812439004"},{"key":"S0022215116000207_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/33.2.115"},{"key":"S0022215116000207_ref16","first-page":"233","article-title":"Ciliary ultrastructure and nasal mucociliary clearance in chronic and allergic rhinitis","volume":"22","author":"Maurizi","year":"1984","journal-title":"Rhinology"},{"key":"S0022215116000207_ref5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.1998.00173.x"},{"key":"S0022215116000207_ref1","first-page":"1152","article-title":"Oral relapsing, aphthous ulcers of the mouth, eye and genitalia caused by a virus [in German]","volume":"105","author":"Beh\u00e7et","year":"1937","journal-title":"Dermatol Wochenschr"},{"key":"S0022215116000207_ref2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215108002703"},{"key":"S0022215116000207_ref19","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199611000-00023"},{"key":"S0022215116000207_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2439-7"},{"key":"S0022215116000207_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.otorri.2013.06.007"},{"key":"S0022215116000207_ref12","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/014556131008900109","article-title":"Nasal mucosal involvement in Beh\u00e7et disease: a study of its incidence and characteristics in 400 patients","volume":"89","author":"Shahram","year":"2010","journal-title":"Ear Nose Throat J"},{"key":"S0022215116000207_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3118-z"},{"key":"S0022215116000207_ref17","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198301000-00013"},{"key":"S0022215116000207_ref20","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2001.00423.x"},{"key":"S0022215116000207_ref14","doi-asserted-by":"publisher","DOI":"10.1097\/00006231-200011000-00007"}],"container-title":["The Journal of Laryngology &amp; 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