{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T18:32:43Z","timestamp":1772649163011,"version":"3.50.1"},"reference-count":23,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T00:00:00Z","timestamp":1458000000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215116000323_sec_a1\"><jats:title>Objective:<\/jats:title><jats:p>Necrotising otitis externa is associated with high morbidity and mortality rates. This study investigated whether temporomandibular joint involvement had any prognostic effect on the course of necrotising otitis externa in patients who had undergone hyperbaric oxygen therapy after failed medical and sometimes surgical therapy.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000323_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>A retrospective case series was conducted of patients in whom antibiotic treatment and surgery had failed, who had been hospitalised for further treatment and hyperbaric oxygen therapy.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000323_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>Twenty-three patients with necrotising otitis externa were identified. The temporomandibular joint was involved in four patients (17 per cent); these patients showed a constant gradual improvement in C-reactive protein and were eventually discharged free of disease, except one patient who was lost to follow up. Four patients (16 per cent) without temporomandibular joint involvement died within 90 days of discharge, while all patients with temporomandibular joint involvement were alive. Three patients (13 per cent) without temporomandibular joint involvement needed recurrent hospitalisation including further hyperbaric oxygen therapy; no patients with temporomandibular joint involvement required such treatment.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000323_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Patients with temporomandibular joint involvement had lower rates of recurrent disease and no mortality. Therefore, we suggest considering temporomandibular joint involvement as a positive prognostic factor in necrotising otitis externa management.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215116000323","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T08:23:58Z","timestamp":1458030238000},"page":"435-439","source":"Crossref","is-referenced-by-count":7,"title":["Temporomandibular joint involvement as a positive clinical prognostic factor in necrotising external otitis"],"prefix":"10.1017","volume":"130","author":[{"given":"E","family":"Yeheskeli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R Abu","family":"Eta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Gavriel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Kleid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Eviatar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2016,3,15]]},"reference":[{"key":"S0022215116000323_ref16","first-page":"235","article-title":"Malignant otitis externa with dysfunction of the temporomandibular articulation [in Spanish]","volume":"44","author":"Rojas Casanova","year":"1993","journal-title":"Acta Otorrinolaringol Esp"},{"key":"S0022215116000323_ref10","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100144196"},{"key":"S0022215116000323_ref19","first-page":"347","article-title":"Hyperbaric oxygen management of chronic staphylococcal osteomyelitis of the temporal bone","volume":"11","author":"Schweitzer","year":"1990","journal-title":"Am J Otol"},{"key":"S0022215116000323_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2012.02.004"},{"key":"S0022215116000323_ref11","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100108813"},{"key":"S0022215116000323_ref21","first-page":"654","article-title":"Huschke's foramen [in French]","volume":"42","author":"Ars","year":"1988","journal-title":"Acta Otorhinolaryngol Belg"},{"key":"S0022215116000323_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(98)90621-8"},{"key":"S0022215116000323_ref17","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-195910000-00006"},{"key":"S0022215116000323_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(03)00471-2"},{"key":"S0022215116000323_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(89)90208-9"},{"key":"S0022215116000323_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(10)80362-3"},{"key":"S0022215116000323_ref4","first-page":"41","article-title":"Malignant otitis externa","volume":"537","author":"Carfrae","year":"2008","journal-title":"Otolaryngol Clin North Am"},{"key":"S0022215116000323_ref20","first-page":"251","article-title":"Persistence of the foramen of Huschke in the adult: an osteological study","volume":"20","author":"Wang","year":"1991","journal-title":"J Otolaryngol"},{"key":"S0022215116000323_ref13","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.132.6.957"},{"key":"S0022215116000323_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(81)90213-8"},{"key":"S0022215116000323_ref1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3174\/ajnr.A2237","article-title":"Diffusion MR imaging features of skull base osteomyelitis compared with skull base malignancy","volume":"32","author":"Ozgen","year":"2011","journal-title":"AJNR Am J Neuroradiol"},{"key":"S0022215116000323_ref22","first-page":"1177","article-title":"Persistence of the foramen of Huschke","volume":"77","author":"Faig-Leite","year":"1999","journal-title":"Dent Res"},{"key":"S0022215116000323_ref5","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0030-6665(20)30316-9","article-title":"Skull base osteomyelitis. 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