{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T22:43:45Z","timestamp":1772491425981,"version":"3.50.1"},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"S2","license":[{"start":{"date-parts":[[2016,5,12]],"date-time":"2016-05-12T00:00:00Z","timestamp":1463011200000},"content-version":"unspecified","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. It provides recommendations on the work up and management of lateral skull base cancer based on the existing evidence base for this rare condition.<\/jats:p><jats:sec id=\"S0022215116000542_sec_a1\"><jats:title>Recommendations<\/jats:title><jats:p>\u2022 All patients with more than one of: chronic otalgia, bloody otorrhoea, bleeding, mass, facial swelling or palsy should be biopsied. (R)<\/jats:p><jats:p>\u2022 Magnetic resonance and computed tomography imaging should be performed. (R)<\/jats:p><jats:p>\u2022 Patients should undergo audiological assessment. (R)<\/jats:p><jats:p>\u2022 Carotid angiography is recommended in select patients. (G)<\/jats:p><jats:p>\u2022 The modified Pittsburg T-staging system is recommended. (G)<\/jats:p><jats:p>\u2022 The minimum operation for cancer involving the temporal bone is a lateral temporal bone resection. (R)<\/jats:p><jats:p>\u2022 Facial nerve rehabilitation should be initiated at primary surgery. (G)<\/jats:p><jats:p>\u2022 Anterolateral thigh free flap is the workhorse flap for lateral skull base defect reconstruction. (G)<\/jats:p><jats:p>\u2022 For patients undergoing surgery for squamous cell carcinoma, at least a superficial parotidectomy and selective neck dissection should be carried out. 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