{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:08:54Z","timestamp":1793329734570,"version":"4.5.0"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"S2","license":[{"start":{"date-parts":[[2016,5,12]],"date-time":"2016-05-12T00:00:00Z","timestamp":1463011200000},"content-version":"unspecified","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. In the absence of high-level evidence base for follow-up practices, the duration and frequency are often at the discretion of local centres. By reviewing the existing literature and collating experience from varying practices across the UK, this paper provides recommendations on the work up and management of lateral skull base cancer based on the existing evidence base for this rare condition.<\/jats:p><jats:sec id=\"S0022215116000645_sec_a1\"><jats:title>Recommendations<\/jats:title><jats:p>\u2022 Patients should be followed up to a minimum of five years with a prolonged follow-up for selected patients. (G)<\/jats:p><jats:p>\u2022 Patients should be followed up at least two monthly in the first two years and three to six monthly in the subsequent years. (G)<\/jats:p><jats:p>\u2022 Patients should be seen in dedicated multidisciplinary head and neck oncology clinics. (G)<\/jats:p><jats:p>\u2022 Patients should be followed up by dedicated multidisciplinary clinical teams. (G)<\/jats:p><jats:p>\u2022 The multidisciplinary follow-up team should include clinical nurse specialists, speech and language therapists, dietitians and other allied health professionals in the role of key workers. (G)<\/jats:p><jats:p>\u2022 Clinical assessment should include adequate clinical examination including fibre-optic rigid or flexible nasopharyngolaryngoscopy. (R)<\/jats:p><jats:p>\u2022 Magnetic resonance imaging and positron emission tomography combined with computed tomography imaging should be used when recurrence is suspected. (R)<\/jats:p><jats:p>\u2022 Narrow band imaging can be used in the follow-up in selected sites. (R)<\/jats:p><jats:p>\u2022 Second primary tumours should be part of rationale of follow-up and therefore adequate screening strategies should be used to detect them. (G)<\/jats:p><jats:p>\u2022 Patients should be educated with regard to the appearance and detection of recurrences. (G)<\/jats:p><jats:p>\u2022 Patients with persistent pain should be investigated to exclude recurrent disease. (R)<\/jats:p><jats:p>\u2022 Patients should be offered support with tobacco and alcohol cessation services. 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