{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:11:46Z","timestamp":1760015506827},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T00:00:00Z","timestamp":1458259200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215116000748_sec_a1\"><jats:title>Objective:<\/jats:title><jats:p>To compare the auditory outcomes of Carina middle-ear implants with those of conventional hearing aids in patients with moderate-to-severe mixed hearing loss.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000748_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>The study comprised nine patients (six males, three females) who underwent middle-ear implantation with Carina fully implantable active middle-ear implants to treat bilateral moderate-to-severe mixed hearing loss. The patients initially used conventional hearing aids and subsequently received the Carina implants. The hearing thresholds with implants and hearing aids were compared.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000748_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>There were no significant differences between: the pre-operative and post-operative air and bone conduction thresholds (<jats:italic>p<\/jats:italic>&gt; 0.05), the thresholds with hearing aids and Carina implants (<jats:italic>p<\/jats:italic>&gt; 0.05), or the pre-operative (mean, 72.8 \u00b1 19 per cent) and post-operative (mean, 69.9 \u00b1 24 per cent) speech discrimination scores (<jats:italic>p<\/jats:italic>&gt; 0.05). One of the patients suffered total sensorineural hearing loss three months following implantation despite an initial 38 dB functional gain. All except one patient showed clinical improvements after implantation according to quality of life questionnaire (Glasgow Benefit Inventory) scores.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000748_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Acceptance of Carina implants is better than with conventional hearing aids in patients with mixed hearing loss, although both yield similar hearing amplification. Cosmetic reasons appear to be critical for patient acceptance.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215116000748","type":"journal-article","created":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T13:58:49Z","timestamp":1458309529000},"page":"340-343","source":"Crossref","is-referenced-by-count":18,"title":["Comparison of Carina active middle-ear implant with conventional hearing aids for mixed hearing loss"],"prefix":"10.1017","volume":"130","author":[{"given":"V A","family":"Sava\u015f","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"G\u00fcnd\u00fcz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Karamert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Cevizci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"D\u00fczl\u00fc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Tutar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y A","family":"Bayazit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2016,3,18]]},"reference":[{"key":"S0022215116000748_ref16","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31802dfc59"},{"key":"S0022215116000748_ref15","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31802b6561"},{"key":"S0022215116000748_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.12.002"},{"key":"S0022215116000748_ref13","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181c34898"},{"key":"S0022215116000748_ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000171479"},{"key":"S0022215116000748_ref8","doi-asserted-by":"publisher","DOI":"10.1080\/14992020600840903"},{"key":"S0022215116000748_ref7","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0030-6665(20)30576-4","article-title":"The round window electromagnetic implantable hearing aid approach","volume":"28","author":"Spindel","year":"1995","journal-title":"Otolaryngol Clin North Am"},{"key":"S0022215116000748_ref6","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0030-6665(20)30575-2","article-title":"Piezoelectric middle ear implant preserving the ossicular chain","volume":"28","author":"Dumon","year":"1995","journal-title":"Otolaryngol Clin North Am"},{"key":"S0022215116000748_ref9","doi-asserted-by":"publisher","DOI":"10.1080\/00016480410016298"},{"key":"S0022215116000748_ref4","first-page":"13","volume-title":"Localization of Sound: Theory and Applications","author":"Shaw","year":"1979"},{"key":"S0022215116000748_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181656969"},{"key":"S0022215116000748_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.03.012"},{"key":"S0022215116000748_ref1","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1097\/MAO.0b013e31825f230d","article-title":"A systematic review of the safety and effectiveness of fully implantable middle ear hearing devices: the Carina and Esteem systems","volume":"33","author":"Klein","year":"2012","journal-title":"Otol Neurotol"},{"key":"S0022215116000748_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(05)70333-9"},{"key":"S0022215116000748_ref2","first-page":"79","article-title":"Fully implantable Otologics MET Carina device for the treatment of sensorineural hearing loss. 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