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Otol."],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215116000943_sec_a1\"><jats:title>Objectives:<\/jats:title><jats:p>To gather and analyse information concerning the aetiology and pathology of otitis media with effusion in adults.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000943_sec_a2\"><jats:title>Method:<\/jats:title><jats:p>A review of the English language literature from 1970 to the present was conducted.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000943_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>The available evidence suggests that otitis media with effusion in adult life is best viewed as a syndrome with a number of causes, including: infiltration of the eustachian tube by nasopharyngeal carcinoma and other local malignancies; changes in the middle ear and eustachian tube induced by radiotherapy; and systemic disease.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116000943_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>There is now a body of evidence specifically related to the aetiology and pathology of otitis media with effusion in adult life. 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