{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:22:26Z","timestamp":1791397346869,"version":"4.3.3"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T00:00:00Z","timestamp":1463529600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215116001201_sec_a1\"><jats:title>Objective:<\/jats:title><jats:p>To calculate the financial burden of recurrent respiratory papilloma. This study is UK-based, where up until now no financial estimates have been calculated for this group of patients.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116001201_sec_a2\"><jats:title>Background:<\/jats:title><jats:p>Recurrent respiratory papilloma is caused by the human papilloma virus (subtypes 6 and 11). The burden for the patient and the healthcare system is significant given the recurrent nature of the disease.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116001201_sec_a3\"><jats:title>Methods:<\/jats:title><jats:p>Data were collected, using a questionnaire completed during routine clinical follow up, from a single centre managing recurrent respiratory papilloma in Glasgow, Scotland. Cost information was sourced from the Scottish Government's Information Services Division.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116001201_sec_a4\"><jats:title>Results:<\/jats:title><jats:p>Fourteen patients with active recurrent respiratory papilloma between 2013 and 2014 were identified. The direct measurable cost to NHS Greater Glasgow and Clyde amounted to \u00a3107 478.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116001201_sec_a5\"><jats:title>Conclusion:<\/jats:title><jats:p>Recurrent respiratory papilloma is a benign condition, but the financial implications of diagnosis are significant. Recurrent respiratory papilloma has a natural history of relapse and remission, and patients may require healthcare input over a period of several years.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215116001201","type":"journal-article","created":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T09:09:33Z","timestamp":1463562573000},"page":"645-649","source":"Crossref","is-referenced-by-count":6,"title":["Economic impact of recurrent respiratory papillomas in a UK adult population"],"prefix":"10.1017","volume":"130","author":[{"given":"A","family":"Harrison","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Montgomery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F B","family":"Macgregor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,5,18]]},"reference":[{"key":"S0022215116001201_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23673"},{"key":"S0022215116001201_ref11","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/86.11.859"},{"key":"S0022215116001201_ref8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108293250904"},{"key":"S0022215116001201_ref12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-11-13"},{"key":"S0022215116001201_ref10","doi-asserted-by":"publisher","DOI":"10.1177\/000348949410300407"},{"key":"S0022215116001201_ref5","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2013.867457"},{"key":"S0022215116001201_ref9","doi-asserted-by":"publisher","DOI":"10.1177\/000348940511400608"},{"key":"S0022215116001201_ref4","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S81825"},{"key":"S0022215116001201_ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198808183190704"},{"key":"S0022215116001201_ref17","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit436"},{"key":"S0022215116001201_ref14","unstructured":"Medicines Complete. Human Papilloma Vaccines. In: https:\/\/www.medicinescomplete.com\/mc\/bnf\/current\/DMD10880211000001104.htm?q=gardasil&t=search&ss=text&p=1#DMD10880211000001104 [26 November 2015]"},{"key":"S0022215116001201_ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0463.2010.02619.x"},{"key":"S0022215116001201_ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0546-z"},{"key":"S0022215116001201_ref18","doi-asserted-by":"publisher","DOI":"10.1258\/0956462041558168"},{"key":"S0022215116001201_ref3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2000.00345.x"},{"key":"S0022215116001201_ref13","unstructured":"ISD Scotland. Acute Surgical Speciality Costs. In: http:\/\/www.isdscotland.org\/Health-Topics\/Finance\/Costs\/Detailed-Tables\/Speciality-Costs\/Acute-Surgical.asp [25 November 2015]"},{"key":"S0022215116001201_ref15","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200301000-00026"},{"key":"S0022215116001201_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23189"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215116001201","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T02:23:01Z","timestamp":1555640581000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215116001201\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,18]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S0022215116001201"],"URL":"https:\/\/doi.org\/10.1017\/s0022215116001201","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,18]]}}}