{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T22:21:48Z","timestamp":1777328508459,"version":"3.51.4"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T00:00:00Z","timestamp":1478563200000},"content-version":"unspecified","delay-in-days":7,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215116009087_sec_a1\"><jats:title>Objective:<\/jats:title><jats:p>This study aimed to compare two sampling methods for nasal nitric oxide in healthy individuals and allergic rhinitis patients, and to examine the within-subject reliability of nasal nitric oxide measurement.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116009087_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>The study included 23 allergic rhinitis patients without concomitant asthma and 10 healthy individuals. For all participants, nitric oxide levels were measured non-invasively from the lungs through the mouth (i.e. the oral fractional exhaled nitric oxide) and the nose. Nasal nitric oxide was measured by two different methods: (1) nasal aspiration via one nostril during breath holding and (2) single-breath quiet exhalation against resistance through a tight facemask (i.e. the nasal fractional exhaled nitric oxide).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116009087_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>Compared with healthy participants, allergic rhinitis patients had significantly higher average oral and nasal nitric oxide levels. All methods of nitric oxide measurement had excellent reliability.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116009087_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Nasal nitric oxide measurement is a useful and reliable clinical tool for diagnosing allergic rhinitis in patients without asthma in an out-patient setting.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215116009087","type":"journal-article","created":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T11:00:30Z","timestamp":1478602830000},"page":"1064-1071","source":"Crossref","is-referenced-by-count":22,"title":["Measuring nasal nitric oxide in allergic rhinitis patients"],"prefix":"10.1017","volume":"130","author":[{"given":"V S","family":"Nesic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V 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