{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,28]],"date-time":"2025-12-28T08:04:48Z","timestamp":1766909088960},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"S2","license":[{"start":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T00:00:00Z","timestamp":1480896000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215116009592_sec_a1\"><jats:title>Background:<\/jats:title><jats:p>Olfactory neuroblastoma is a rare sinonasal malignancy, with poorly defined treatment protocols. Management at a tertiary centre was retrospectively evaluated to inform future treatment and follow up.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116009592_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>Cases treated with curative intent (2000\u20132014) were included. Data were collected, and overall and disease-free survival rates were calculated.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116009592_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>Eleven cases were identified, with a median follow up of 87 months. One patient was Kadish stage A, one was stage B, eight were stage C and one was stage D. The latter patient underwent chemoradiotherapy alone. The remaining patients proceeded to: endoscopic-assisted wide local excision (<jats:italic>n<\/jats:italic> = 2), anterior craniofacial resection (<jats:italic>n<\/jats:italic> = 4) or endoscopic craniofacial resection (<jats:italic>n<\/jats:italic> = 4). No patients had primary nodal disease or elective neck treatment. One patient had neoadjuvant chemoradiation. Six patients had post-operative radiotherapy; three received adjuvant chemotherapy. Two patients had late cervical node failure, and proceeded to neck dissection and post-operative radiotherapy. Two patients had late local recurrence. Ten-year overall and disease-free survival rates were 68.2 and 46.7 per cent, respectively.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215116009592_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Longer-term follow up is supported given the incidence of late regional and local recurrence. Prophylactic treatment of cervical nodes in locally advanced disease is an area for further investigation.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215116009592","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T05:41:59Z","timestamp":1480916519000},"page":"S29-S34","source":"Crossref","is-referenced-by-count":10,"title":["Olfactory neuroblastoma: 14-year experience at an Australian tertiary centre and the role for longer-term surveillance"],"prefix":"10.1017","volume":"131","author":[{"given":"C","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Potter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Porceddu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Panizza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2016,12,5]]},"reference":[{"key":"S0022215116009592_ref14","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199805000-00045"},{"key":"S0022215116009592_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20280"},{"key":"S0022215116009592_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.03.036"},{"key":"S0022215116009592_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.12.038"},{"key":"S0022215116009592_ref18","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1390011"},{"key":"S0022215116009592_ref19","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200304000-00009"},{"key":"S0022215116009592_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(02)02941-3"},{"key":"S0022215116009592_ref25","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2014.944271"},{"key":"S0022215116009592_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2012.08.005"},{"key":"S0022215116009592_ref1","first-page":"2683","article-title":"Esthesioneuroblastoma: a general review of the cases published since the discovery of the tumour in 1924","volume":"17","author":"Broich","year":"1997","journal-title":"Anticancer Res"},{"key":"S0022215116009592_ref16","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815620173"},{"key":"S0022215116009592_ref21","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20166"},{"key":"S0022215116009592_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197603)37:3<1571::AID-CNCR2820370347>3.0.CO;2-L"},{"key":"S0022215116009592_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-003-1089-x"},{"key":"S0022215116009592_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-014-0423-z"},{"key":"S0022215116009592_ref6","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199305000-00002"},{"key":"S0022215116009592_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2015.02.008"},{"key":"S0022215116009592_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24562"},{"key":"S0022215116009592_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2013.01.106"},{"key":"S0022215116009592_ref13","first-page":"2306","article-title":"Comparison of outcomes for open versus endoscopic approaches for olfactory neuroblastoma: a systematic review and individual participant data meta-analysis","volume":"30","author":"Fu","year":"2015","journal-title":"Head Neck"},{"key":"S0022215116009592_ref7","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199208000-00001"},{"key":"S0022215116009592_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/hed.1107"},{"key":"S0022215116009592_ref17","doi-asserted-by":"publisher","DOI":"10.3171\/2010.2.JNS091897"},{"key":"S0022215116009592_ref22","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880130409"},{"key":"S0022215116009592_ref24","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10247"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215116009592","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T16:49:10Z","timestamp":1555519750000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215116009592\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,5]]},"references-count":25,"journal-issue":{"issue":"S2","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["S0022215116009592"],"URL":"https:\/\/doi.org\/10.1017\/s0022215116009592","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,5]]}}}