{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T16:18:29Z","timestamp":1783700309362,"version":"3.55.0"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2017,2,14]],"date-time":"2017-02-14T00:00:00Z","timestamp":1487030400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215117000056_sec_a1\"><jats:title>Objective:<\/jats:title><jats:p>To search for studies on tongue\u2013lip adhesion and tongue repositioning used as isolated treatments for obstructive sleep apnoea in children with Pierre Robin sequence.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117000056_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>A systematic literature search of PubMed\/Medline and three additional databases, from inception through to 8 July 2016, was performed by two authors.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117000056_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>Seven studies with 90 patients (59 tongue\u2013lip adhesion and 31 tongue repositioning patients) met the inclusion criteria. Tongue\u2013lip adhesion reduced the mean (\u00b1 standard deviation) apnoea\/hypopnoea index from 30.8 \u00b1 22.3 to 15.4 \u00b1 18.9 events per hour (50 per cent reduction). The apnoea\/hypopnoea index mean difference for tongue\u2013lip adhesion was \u221215.28 events per hour (95 per cent confidence interval = \u221230.70 to 0.15;<jats:italic>p<\/jats:italic>= 0.05). Tongue\u2013lip adhesion improved the lowest oxygen saturation from 75.8 \u00b1 6.8 to 84.4 \u00b1 7.3 per cent. Tongue repositioning reduced the apnoea\/hypopnoea index from 46.5 to 17.4 events per hour (62.6 per cent reduction). Tongue repositioning improved the mean oxygen saturation from 90.8 \u00b1 1.2 to 95.0 \u00b1 0.5 per cent.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117000056_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Tongue\u2013lip adhesion and tongue repositioning can improve apnoea\/hypopnoea index and oxygenation parameters in children with Pierre Robin sequence and obstructive sleep apnoea.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215117000056","type":"journal-article","created":{"date-parts":[[2017,2,14]],"date-time":"2017-02-14T04:08:53Z","timestamp":1487045333000},"page":"378-383","source":"Crossref","is-referenced-by-count":22,"title":["Tongue\u2013lip adhesion and tongue repositioning for obstructive sleep apnoea in Pierre Robin sequence: A systematic review and meta-analysis"],"prefix":"10.1017","volume":"131","author":[{"given":"M","family":"Camacho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M W","family":"Noller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Zaghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L K","family":"Reckley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Fernandez-Salvador","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D K","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2017,2,14]]},"reference":[{"key":"S0022215117000056_ref15","doi-asserted-by":"publisher","DOI":"10.1597\/10-173"},{"key":"S0022215117000056_ref11","first-page":"151","article-title":"Polysomnographic indications for surgical intervention in Pierre Robin sequence: acute airway management and follow-up studies after repair and take-down of tongue-lip adhesion","volume":"25","author":"Freed","year":"1988","journal-title":"Cleft Palate J"},{"key":"S0022215117000056_ref6","unstructured":"Review Manager (RevMan) [computer program], version 5.3. 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