{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,15]],"date-time":"2026-11-15T00:30:08Z","timestamp":1794702608129,"version":"4.9.1"},"reference-count":39,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T00:00:00Z","timestamp":1489968000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215117000597_sec_a1\"><jats:title>Objective:<\/jats:title><jats:p>To identify <jats:italic>Helicobacter pylori<\/jats:italic> infection in tonsillar tissue samples from patients undergoing tonsillectomy for chronic tonsillitis versus tonsillar hypertrophy, and to assess the possible relationships between <jats:italic>H pylori<\/jats:italic> and patients\u2019 sociodemographic data and laryngopharyngeal reflux.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117000597_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>In this prospective study, 97 patients who underwent tonsillectomy were divided into the following 2 groups: patients with chronic tonsillitis (<jats:italic>n<\/jats:italic> = 62) and patients with tonsillar hypertrophy (control group; <jats:italic>n<\/jats:italic> = 35). <jats:italic>H pylori<\/jats:italic> infection in the tonsillar biopsy samples was identified using histochemical and rapid urease tests.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117000597_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>The incidence of <jats:italic>H pylori<\/jats:italic> infection was significantly higher in the chronic tonsillitis group (56.5 per cent) compared to the control group (31.4 per cent). Similar findings were obtained for both subgroups of adults (68.6 <jats:italic>vs<\/jats:italic> 42.3 per cent) and children (40.7 <jats:italic>vs<\/jats:italic> 0.0 per cent). Significant relationships between a positive <jats:italic>H pylori<\/jats:italic> finding and laryngopharyngeal reflux related signs of vocal fold oedema, diffuse laryngeal oedema and hypertrophy of the posterior commissure were revealed.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117000597_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p><jats:italic>H pylori<\/jats:italic> infection may be related to chronic tonsillitis and laryngopharyngeal reflux.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215117000597","type":"journal-article","created":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T13:48:30Z","timestamp":1490017710000},"page":"549-556","source":"Crossref","is-referenced-by-count":29,"title":["<i>Helicobacter pylori<\/i> in the tonsillar tissue: a possible association with chronic tonsillitis and laryngopharyngeal reflux"],"prefix":"10.1017","volume":"131","author":[{"given":"N","family":"Siupsinskiene","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Katutiene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Jonikiene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Janciauskas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Vaitkus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2017,3,20]]},"reference":[{"key":"S0022215117000597_ref12","first-page":"85","article-title":"Investigation of Helicobacter pylori colonization in pharyngeal and palatine tonsils with rapid urease test and immunohistochemical analysis [in Turkish]","volume":"18","author":"Dagtekin-Ergur","year":"2008","journal-title":"Kulak Burun Bogaz Ihtis Derg"},{"key":"S0022215117000597_ref27","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.11.1225"},{"key":"S0022215117000597_ref32","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-4579(00)00312-9"},{"key":"S0022215117000597_ref39","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1177\/014556131309200311","article-title":"Does tonsillectomy affect the outcome of drug treatment for the eradication of gastric H pylori infection? 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