{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T06:28:11Z","timestamp":1762324091459},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"S2","license":[{"start":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T00:00:00Z","timestamp":1492387200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215117000779_sec_a1\"><jats:title>Background:<\/jats:title><jats:p>Sudden sensorineural hearing loss is a rare otological condition with potential for dire outcomes including permanent hearing loss. Although the majority of cases are deemed idiopathic, bilateral sudden sensorineural hearing loss represents a rare subset typically related to systemic conditions, with higher morbidity and mortality. A controversial association with acute otitis media has been reported, with few bilateral cases published in the literature.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117000779_sec_a2\"><jats:title>Case report:<\/jats:title><jats:p>A very rare case of bilateral sudden sensorineural hearing loss associated with acute otitis media is described, with a review of the literature.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117000779_sec_a3\"><jats:title>Conclusion:<\/jats:title><jats:p>The limited evidence available suggests that acute otitis media with tinnitus and\/or bacterial pathology may have an increased risk of sudden sensorineural hearing loss, which is consistent with the case described. Although there is no sufficiently powered published evidence to provide definitive treatment guidelines, the literature reviewed suggests that early myringotomy and antibiotics may greatly improve treatment outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215117000779","type":"journal-article","created":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T07:50:07Z","timestamp":1492415407000},"page":"S57-S61","source":"Crossref","is-referenced-by-count":10,"title":["Acute otitis media associated bilateral sudden hearing loss: case report and literature review"],"prefix":"10.1017","volume":"131","author":[{"given":"A","family":"Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Gutteridge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Cronin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,4,17]]},"reference":[{"key":"S0022215117000779_ref17","doi-asserted-by":"publisher","DOI":"10.1177\/000348941212100204"},{"key":"S0022215117000779_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.05.015"},{"key":"S0022215117000779_ref9","doi-asserted-by":"publisher","DOI":"10.3342\/ceo.2008.1.3.117"},{"key":"S0022215117000779_ref15","doi-asserted-by":"publisher","DOI":"10.1080\/00016480500401043"},{"key":"S0022215117000779_ref19","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2002.00612.x"},{"key":"S0022215117000779_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2675-x"},{"key":"S0022215117000779_ref5","first-page":"157","article-title":"Risk of developing sudden sensorineural hearing loss in patients with acute otitis media: a multicenter retrospective analysis","volume":"4","author":"Akdag","year":"2014","journal-title":"Otolaryngology"},{"key":"S0022215117000779_ref13","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198710000-00015"},{"key":"S0022215117000779_ref20","first-page":"22","article-title":"Acute sensorineural hearing loss caused by Mycoplasma pneumoniae","volume":"522","author":"Okada","year":"1995","journal-title":"Acta Otolaryngol Suppl"},{"key":"S0022215117000779_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/S002221511300306X"},{"key":"S0022215117000779_ref7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.1999.00237.x"},{"key":"S0022215117000779_ref1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812436449"},{"key":"S0022215117000779_ref12","first-page":"237","volume-title":"Scott-Brown's Otolaryngology","author":"Ludman","year":"1987"},{"key":"S0022215117000779_ref21","doi-asserted-by":"publisher","DOI":"10.1177\/1084713811408349"},{"key":"S0022215117000779_ref18","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2005.46.1.161"},{"key":"S0022215117000779_ref10","doi-asserted-by":"publisher","DOI":"10.3109\/00016480903311252"},{"key":"S0022215117000779_ref8","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1128\/IAI.63.4.1305-1310.1995","article-title":"Breakdown of the round window membrane permeability barrier evoked by streptolysin O: possible etiologic role in development of sensorineural hearing loss in acute otitis media","volume":"63","author":"Engel","year":"1995","journal-title":"Infect Immun"},{"key":"S0022215117000779_ref2","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1002\/lary.20873","article-title":"Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss","volume":"120","author":"Chau","year":"2010","journal-title":"Laryngoscope"},{"key":"S0022215117000779_ref14","doi-asserted-by":"publisher","DOI":"10.1258\/0022215001903654"},{"key":"S0022215117000779_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0739-0"},{"key":"S0022215117000779_ref11","doi-asserted-by":"publisher","DOI":"10.1177\/00034894900990S610"}],"container-title":["The Journal of Laryngology &amp; 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