{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T12:10:42Z","timestamp":1774267842416,"version":"3.50.1"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215117001086_sec_a1\"><jats:title>Objectives:<\/jats:title><jats:p>To identify and evaluate cranial magnetic resonance imaging findings associated with M\u00e9ni\u00e8re's disease.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117001086_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>Seventy-eight patients with a documented diagnosis of M\u00e9ni\u00e8re's disease and 35 controls underwent 1.5 T or 3 T magnetic resonance imaging of the brain. Patients also underwent otological, vestibular and audiometric examinations.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117001086_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>Lack of visualisation of the left and right vestibular aqueducts was identified as statistically significant amongst M\u00e9ni\u00e8re's disease patients (left,<jats:italic>p<\/jats:italic>= 0.0001, odds ratio = 0.02; right,<jats:italic>p<\/jats:italic>= 0.0004, odds ratio = 0.03). Both vestibular aqueducts were of abnormal size in the M\u00e9ni\u00e8re's disease group, albeit with left-sided significance (left,<jats:italic>p<\/jats:italic>= 0.008, odds ratio = 10.91; right,<jats:italic>p<\/jats:italic>= 0.49, odds ratio = 2.47).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117001086_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Lack of vestibular aqueduct visualisation on magnetic resonance imaging was statistically significant in M\u00e9ni\u00e8re's disease patients compared to the general population. The study findings suggest that magnetic resonance imaging can be useful to rule out retrocochlear pathology and provide radiological data to support the clinical diagnosis of M\u00e9ni\u00e8re's disease.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215117001086","type":"journal-article","created":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T07:54:47Z","timestamp":1496735687000},"page":"602-607","source":"Crossref","is-referenced-by-count":11,"title":["Magnetic resonance imaging findings in M\u00e9ni\u00e8re's disease"],"prefix":"10.1017","volume":"131","author":[{"given":"V A","family":"Patel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B S","family":"Oberman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T T","family":"Zacharia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Isildak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"key":"S0022215117001086_ref27","doi-asserted-by":"crossref","first-page":"E16","DOI":"10.3174\/ajnr.A2262","article-title":"Diffuse pachymeningeal enhancement and subdural and subarachnoid space opacification on delayed postcontrast fluid-attenuated inversion recovery imaging in spontaneous intracranial hypotension: visualizing the Monro-Kellie hypothesis","volume":"32","author":"George","year":"2011","journal-title":"AJNR Am J Neuroradiol"},{"key":"S0022215117001086_ref16","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.9.1366"},{"key":"S0022215117001086_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/BF00464632"},{"key":"S0022215117001086_ref5","doi-asserted-by":"publisher","DOI":"10.1080\/00016480902729868"},{"key":"S0022215117001086_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2009.09.015"},{"key":"S0022215117001086_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.otorri.2014.05.002"},{"key":"S0022215117001086_ref29","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414534329"},{"key":"S0022215117001086_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e32836463bc"},{"key":"S0022215117001086_ref28","first-page":"258","article-title":"Otologic manifestations of pseudotumor cerebri","volume":"20","author":"Murphy","year":"1991","journal-title":"J Otolaryngol"},{"key":"S0022215117001086_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2010.05.001"},{"key":"S0022215117001086_ref6","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31815c1a61"},{"key":"S0022215117001086_ref30","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-9-29"},{"key":"S0022215117001086_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70102-8"},{"key":"S0022215117001086_ref2","doi-asserted-by":"publisher","DOI":"10.3109\/00016480903382808"},{"key":"S0022215117001086_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2007.04.011"},{"key":"S0022215117001086_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182868818"},{"key":"S0022215117001086_ref14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.3233\/VES-2011-0423","article-title":"Epidemiological evidence for a link between vertigo and migraine","volume":"21","author":"von Brevern","year":"2011","journal-title":"J Vestib Res"},{"key":"S0022215117001086_ref25","doi-asserted-by":"publisher","DOI":"10.1177\/0268355514526871"},{"key":"S0022215117001086_ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-009-1122-5"},{"key":"S0022215117001086_ref23","first-page":"1165","article-title":"Multiple sclerosis: the role of MR imaging","volume":"27","author":"Ge","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"S0022215117001086_ref18","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199611000-00010"},{"key":"S0022215117001086_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(83)80071-4"},{"key":"S0022215117001086_ref15","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1177\/014556130908801105","article-title":"Epidemiologic study to explore links between M\u00e9ni\u00e8re syndrome and migraine headache","volume":"88","author":"Gopen","year":"2009","journal-title":"Ear Nose Throat J"},{"key":"S0022215117001086_ref19","first-page":"1","volume-title":"Hydrocephalus and the Cerebrospinal Fluid","author":"Milhorat","year":"1972"},{"key":"S0022215117001086_ref12","doi-asserted-by":"publisher","DOI":"10.1177\/000348946707600311"},{"key":"S0022215117001086_ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2841-1"},{"key":"S0022215117001086_ref8","first-page":"80","article-title":"Computed radiographic measurement of the dimensions of the vestibular aqueduct in Meni\u00e8re's disease","volume":"528","author":"Takeda","year":"1997","journal-title":"Acta Otolaryngol Suppl"},{"key":"S0022215117001086_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67144-9"},{"key":"S0022215117001086_ref17","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199105000-00006"},{"key":"S0022215117001086_ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s001060050411"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215117001086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T14:18:52Z","timestamp":1602253132000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215117001086\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,6]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["S0022215117001086"],"URL":"https:\/\/doi.org\/10.1017\/s0022215117001086","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,6]]}}}