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Otol."],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215117001372_sec_a1\"><jats:title>Background:<\/jats:title><jats:p>Molecular categorisation may explain the wide variation in the clinical characteristics of juvenile nasopharyngeal angiofibroma.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117001372_sec_a2\"><jats:title>Methods:<\/jats:title><jats:p>Variations in molecular markers in juvenile nasopharyngeal angiofibroma in an Indian population were investigated and compared with global reports.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117001372_sec_a3\"><jats:title>Results:<\/jats:title><jats:p>Variable molecular marker expression was demonstrated at the regional and global levels. A wide variation in molecular characteristics is evident. Molecular data have been reported for only 11 countries, indicating a clear geographical bias. Only 58 markers have been studied, and most are yet to be validated.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215117001372_sec_a4\"><jats:title>Conclusion:<\/jats:title><jats:p>Research into the molecular epidemiology of juvenile nasopharyngeal angiofibroma is still in its infancy. Although the molecular variation is not well understood, data obtained so far have prompted important research questions. 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