{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T10:19:43Z","timestamp":1785493183563,"version":"3.56.0"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"unspecified","delay-in-days":4,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2018,9]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Although melioidosis in the head and neck region is uncommon, it is a potentially life-threatening infection. Thus, early diagnosis and proper management are very important.<\/jats:p><\/jats:sec>Objectives<\/jats:title>To report the clinical presentation and management of melioidosis in the head and neck.<\/jats:p><\/jats:sec>Method<\/jats:title>A retrospective study was conducted from 1 January 2013 to 31 October 2016 in Mukdahan Hospital, Thailand. Case records of patients who had presented with culture-positive melioidosis were analysed.<\/jats:p><\/jats:sec>Results<\/jats:title>Medical records of 49 patients (23 males and 26 females) were analysed. Patients ranged in age from 1 to 75 years. Clinical presentations included 22 parotid abscesses, 16 neck abscesses and 11 suppurative lymphadenitis cases. Only 35 patients (71 per cent) had high indirect haemagglutination assay titres of \u2265 1:160 (95 per cent confidence interval = 45.35\u201388.28). Almost half of the patients received intravenous ceftazidime and subsequently oral co-trimoxazole. Oral antibiotic regimens were prescribed for mild localised melioidosis. Overall, 95.65 per cent of patients were in remission and no relapses were observed (95 per cent confidence interval = 85.47\u201398.80).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Careful clinical correlation and proper investigation are required to establish an early diagnosis of melioidosis and to initiate appropriate treatment.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215118001391","type":"journal-article","created":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T06:24:15Z","timestamp":1536128655000},"page":"827-831","source":"Crossref","is-referenced-by-count":10,"title":["Clinical presentation and treatment of melioidosis in the head and neck region"],"prefix":"10.1017","volume":"132","author":[{"given":"K","family":"Mahawerawat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Kasemsiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2018,9,5]]},"reference":[{"key":"S0022215118001391_ref4","first-page":"471","article-title":"Melioidosis of the head and neck","volume":"56","author":"Lim","year":"2001","journal-title":"Med J Malaysia"},{"key":"S0022215118001391_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62143-1"},{"key":"S0022215118001391_ref3","first-page":"363","article-title":"Monthly rainfall and severity of melioidosis in Nakhon Phanom, Northeastern Thailand","volume":"17","author":"Tanwisaid","year":"2008","journal-title":"J Health Sci"},{"key":"S0022215118001391_ref9","first-page":"2763","article-title":"Melioidosis: a review","volume":"14","author":"Foong","year":"2014","journal-title":"Rural Remote Health"},{"key":"S0022215118001391_ref8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1204699"},{"key":"S0022215118001391_ref2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/23.5.1082"},{"key":"S0022215118001391_ref10","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.15-0114"},{"key":"S0022215118001391_ref11","first-page":"17","article-title":"Indirect hemagglutination test for the diagnosis of melioidosis in Ubon Ratchathani","volume":"14","author":"Teparrugkul","year":"1997","journal-title":"J Infect Dis Antimicrob Agents"},{"key":"S0022215118001391_ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-017-2626-5"},{"key":"S0022215118001391_ref17","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2008.78.208"},{"key":"S0022215118001391_ref6","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116008276"},{"key":"S0022215118001391_ref15","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/121845"},{"key":"S0022215118001391_ref5","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2016-218606"},{"key":"S0022215118001391_ref12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004847"},{"key":"S0022215118001391_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/159.5.890"},{"key":"S0022215118001391_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2014.01.005"},{"key":"S0022215118001391_ref7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012485"},{"key":"S0022215118001391_ref18","doi-asserted-by":"publisher","DOI":"10.1086\/507632"}],"container-title":["The Journal of Laryngology & Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215118001391","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,13]],"date-time":"2019-04-13T21:38:00Z","timestamp":1555191480000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215118001391\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":18,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S0022215118001391"],"URL":"https:\/\/doi.org\/10.1017\/s0022215118001391","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]}}}