{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:06:17Z","timestamp":1780499177085,"version":"3.54.1"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T00:00:00Z","timestamp":1543449600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215118002037_sec_a1\"><jats:title>Background<\/jats:title><jats:p>Benign paroxysmal positional vertigo is a common inner-ear pathology, characterised by episodic vertigo lasting for a few seconds that is associated with sudden change in the head position. Benign paroxysmal positional vertigo is treated with canalolith repositioning manoeuvres. Intractable vertigo describes a small group of patients who either do not improve with canalolith repositioning manoeuvres (persistent cases) or who relapse after improvement of initial symptoms (recurrent cases). These cases are difficult to treat and may have to be treated surgically.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215118002037_sec_a2\" sec-type=\"cases\"><jats:title>Case reports<\/jats:title><jats:p>This paper reports two cases of intractable posterior canal benign paroxysmal positional vertigo that were treated with intratympanic dexamethasone injections on an interval basis.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215118002037_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Both patients showed good control of their vertiginous symptoms, with negative Dix\u2013Hallpike test findings following the intervention.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215118002037_sec_a4\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>The findings support an underlying inflammatory pathology in intractable benign paroxysmal positional vertigo; intratympanic steroids should be considered as an intermediate option before proceeding to a definitive surgical intervention.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215118002037","type":"journal-article","created":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T08:19:55Z","timestamp":1543479595000},"page":"1147-1149","source":"Crossref","is-referenced-by-count":7,"title":["A novel use of intratympanic dexamethasone for intractable posterior canal benign paroxysmal positional vertigo: report of two cases"],"prefix":"10.1017","volume":"132","author":[{"given":"A","family":"Kelkar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2018,11,29]]},"reference":[{"key":"S0022215118002037_ref7","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812454642"},{"key":"S0022215118002037_ref19","first-page":"230","article-title":"Effect of transtympanic injection of steroids on cochlear blood flow, auditory sensitivity, and histology in the guinea pig","volume":"19","author":"Shirway","year":"1988","journal-title":"Am J Otol"},{"key":"S0022215118002037_ref11","first-page":"434","article-title":"Diagnosing pathologies in the area of otolith apparatus [in German]","volume":"2","author":"Barany","year":"1921","journal-title":"Acta Otolaryngol"},{"key":"S0022215118002037_ref17","first-page":"564","article-title":"Intratympanic injection of dexamethasone: time course of inner ear distribution and conversion to its active form","volume":"27","author":"Hargunani","year":"2006","journal-title":"Otol Neurotol"},{"key":"S0022215118002037_ref12","doi-asserted-by":"publisher","DOI":"10.1177\/000348945206100403"},{"key":"S0022215118002037_ref14","doi-asserted-by":"publisher","DOI":"10.1177\/019459988008800514"},{"key":"S0022215118002037_ref6","doi-asserted-by":"publisher","DOI":"10.5152\/iao.2016.3014"},{"key":"S0022215118002037_ref2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812457134"},{"key":"S0022215118002037_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70010-2"},{"key":"S0022215118002037_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.wjorl.2015.11.001"},{"key":"S0022215118002037_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000154723.55044.b5"},{"key":"S0022215118002037_ref9","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215112000758"},{"key":"S0022215118002037_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.10.035"},{"key":"S0022215118002037_ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1969.00770030767020"},{"key":"S0022215118002037_ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000101541"},{"key":"S0022215118002037_ref8","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1055\/s-0037-1599784","article-title":"Surgical treatment for recurrent benign paroxysmal positional vertigo","volume":"21","author":"Corvera Behar","year":"2017","journal-title":"Int Arch Otorhinolaryngol"},{"key":"S0022215118002037_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.05.015"},{"key":"S0022215118002037_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181cabd77"},{"key":"S0022215118002037_ref3","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000313378.77444.ac"},{"key":"S0022215118002037_ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000055734"},{"key":"S0022215118002037_ref18","doi-asserted-by":"publisher","DOI":"10.1080\/00016480701558906"}],"container-title":["The Journal of Laryngology &amp; 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