{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T22:17:43Z","timestamp":1771798663642,"version":"3.50.1"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215119000033_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>Adenotonsillectomy is frequently performed for obstructive sleep apnoea, but is associated with post-operative respiratory morbidity. This study assessed the effect of paediatric Otrivine (0.05 per cent xylometazoline hydrochloride) on post-operative respiratory compromise.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215119000033_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>Paediatric patients undergoing adenotonsillectomy for obstructive sleep apnoea were included. The control group (<jats:italic>n<\/jats:italic> = 24) received no intervention and the intervention group (<jats:italic>n<\/jats:italic> = 25) received intra-operative paediatric Otrivine during induction using a nasal patty. Post-operative outcomes included pain, respiratory distress signs and medical intervention level required (simple, intermediate and major).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215119000033_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Post-operative respiratory distress signs were exhibited by 4 per cent of the Otrivine group and 21 per cent of the control group. Sixty-eight per cent of the Otrivine group required simple medical interventions post-operatively, compared to 42 per cent of the control group. In the Otrivine group, 4 per cent required intermediate interventions; none required major interventions. In the control group, 12.5 per cent required both intermediate and major interventions. Fifty per cent of the control group reported pain post-operatively, compared with 40 per cent in the Otrivine group.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215119000033_sec_a4\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>Intra-operative paediatric Otrivine may reduce post-operative respiratory compromise in paediatric patients undergoing adenotonsillectomy for obstructive sleep apnoea. A randomised controlled trial is required.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215119000033","type":"journal-article","created":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T05:57:56Z","timestamp":1549000676000},"page":"110-114","source":"Crossref","is-referenced-by-count":3,"title":["Investigating the effect of a nasal decongestant on post-adenotonsillectomy respiratory complications in 25 paediatric patients with obstructive sleep apnoea: a pilot study"],"prefix":"10.1017","volume":"133","author":[{"given":"E","family":"Shamil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M J","family":"Rouhani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A C","family":"Panayi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Tysome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Jonas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2019,2,1]]},"reference":[{"key":"S0022215119000033_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(87)90088-7"},{"key":"S0022215119000033_ref2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1672"},{"key":"S0022215119000033_ref14","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq205"},{"key":"S0022215119000033_ref7","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200202000-00015"},{"key":"S0022215119000033_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000040"},{"key":"S0022215119000033_ref4","first-page":"CD003136","article-title":"Adenotonsillectomy for obstructive sleep apnea in children","volume":"4","author":"Lim","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"S0022215119000033_ref12","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000244318.77377.67"},{"key":"S0022215119000033_ref1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200708-135MG"},{"key":"S0022215119000033_ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1995.01890050023005"},{"key":"S0022215119000033_ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1992.01880090056017"},{"key":"S0022215119000033_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(99)00109-7"},{"key":"S0022215119000033_ref11","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-1283"},{"key":"S0022215119000033_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2008.00667.x"},{"key":"S0022215119000033_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-010-0941-z"},{"key":"S0022215119000033_ref15","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215108003666"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215119000033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T15:55:22Z","timestamp":1555084522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215119000033\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["S0022215119000033"],"URL":"https:\/\/doi.org\/10.1017\/s0022215119000033","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2]]}}}