{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T02:35:00Z","timestamp":1774319700818,"version":"3.50.1"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T00:00:00Z","timestamp":1554163200000},"content-version":"unspecified","delay-in-days":1,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2019,4]]},"abstract":"Abstract<\/jats:title>Objectives<\/jats:title>Animal studies have suggested that exposure of the middle ear to topical local anaesthesia may be ototoxic. This study aimed to report sensorineural hearing outcomes and patients\u2019 satisfaction in those who underwent myringotomy and ventilation tube insertion using topical local anaesthesia.<\/jats:p><\/jats:sec>Methods<\/jats:title>Twenty-nine patients (32 ears) were operated on. Pre- and post-operative audiology findings were compared. A Likert-type questionnaire on treatment satisfaction was completed at the end of the procedure.<\/jats:p><\/jats:sec>Results<\/jats:title>Median patient age was 55 years (range, 27\u201388 years). Pre- and post-operative bone conduction pure tone averages were 26.76 dB and 25.26 dB respectively (mean reduction of \u22121.22 dB, 95 per cent confidence interval of \u22125.91 to 8.13 dB; p<\/jats:italic> = 0.7538). One ear (3 per cent) had a reduction in pure tone average of 10 dB.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The results suggest that sensorineural hearing loss is not a complication of ear exposure to topical local anaesthesia during myringotomy and ventilation tube insertion. The procedure was well perceived.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215119000288","type":"journal-article","created":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T04:30:15Z","timestamp":1554179415000},"page":"285-288","source":"Crossref","is-referenced-by-count":2,"title":["Assessing ototoxicity and patients\u2019 satisfaction of topical local anaesthesia in myringotomy and ventilation tube insertion"],"prefix":"10.1017","volume":"133","author":[{"given":"S","family":"Marzouk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Al-lami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Sykes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I J","family":"Nixon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2019,4,2]]},"reference":[{"key":"S0022215119000288_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1988.tb00322.x"},{"key":"S0022215119000288_ref10","first-page":"49","article-title":"Toxic effects on inner ear of noxious agents passing through the round window membrane","volume":"457","author":"Anniko","year":"1989","journal-title":"Acta Otolaryngol Suppl"},{"key":"S0022215119000288_ref1","unstructured":"NHS England. Commissioning Services for People with Hearing Loss: A Framework for Clinical Commissioning Groups. In: https:\/\/www.england.nhs.uk\/wp-content\/uploads\/2016\/07\/HLCF.pdf [2 June 2016]"},{"key":"S0022215119000288_ref2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181776749"},{"key":"S0022215119000288_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200109000-00027"},{"key":"S0022215119000288_ref4","volume-title":"Surgical Management of Otitis Media with Effusion in Children","volume":"31","year":"2008"},{"key":"S0022215119000288_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/BF02114916"},{"key":"S0022215119000288_ref11","first-page":"87","article-title":"Electrophysiological effects of the clinically used local anesthetics lidocaine, lidocaine-prilocaine and phenol on the rat's inner ear","volume":"248","author":"Schmidt","year":"1990","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"S0022215119000288_ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1973.00780020120012"},{"key":"S0022215119000288_ref13","first-page":"193","article-title":"The safety and efficacy of Emla cream topical anesthesia for myringotomy and ventilation tube insertion","volume":"20","author":"Bingham","year":"1991","journal-title":"J Otolaryngol"},{"key":"S0022215119000288_ref12","doi-asserted-by":"publisher","DOI":"10.3109\/00016488909125549"},{"key":"S0022215119000288_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199709000-00006"},{"key":"S0022215119000288_ref9","doi-asserted-by":"publisher","DOI":"10.3109\/00016488809097006"}],"container-title":["The Journal of Laryngology & Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215119000288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,3]],"date-time":"2019-05-03T06:56:28Z","timestamp":1556866588000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215119000288\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S0022215119000288"],"URL":"https:\/\/doi.org\/10.1017\/s0022215119000288","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}