{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T22:05:38Z","timestamp":1773093938623,"version":"3.50.1"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T00:00:00Z","timestamp":1563235200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2019,8]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To determine the impact of pre-operative intratympanic gentamicin injection on the recovery of patients undergoing translabyrinthine resection of vestibular schwannomas.<\/jats:p><\/jats:sec>Methods<\/jats:title>This prospective, case\u2013control pilot study included eight patients undergoing surgical labyrinthectomy, divided into two groups: four patients who received pre-operative intratympanic gentamicin and four patients who did not. The post-operative six-canal video head impulse test responses and length of in-patient stay were assessed.<\/jats:p><\/jats:sec>Results<\/jats:title>The average length of stay was shorter for patients who received intratympanic gentamicin (6.75 days; range, 6\u20137 days) than for those who did not (9.5 days; range, 8\u201311 days) (p<\/jats:italic> = 0.0073). Additionally, the gentamicin group had normal post-operative video head impulse test responses in the contralateral ear, while the non-gentamicin group did not.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Pre-operative intratympanic gentamicin improves the recovery following vestibular schwannoma resection, eliminating, as per the video head impulse test, the impact of labyrinthectomy on the contralateral labyrinth.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215119001002","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T05:21:58Z","timestamp":1563254518000},"page":"668-673","source":"Crossref","is-referenced-by-count":8,"title":["Benefits of pre-labyrinthectomy intratympanic gentamicin: contralateral vestibular responses"],"prefix":"10.1017","volume":"133","author":[{"given":"N","family":"Amiraraghi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Gaggini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J A","family":"Crowther","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Locke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Kontorinis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2019,7,16]]},"reference":[{"key":"S0022215119001002_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182804c41"},{"key":"S0022215119001002_ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2014.00285"},{"key":"S0022215119001002_ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-016-0395-4"},{"key":"S0022215119001002_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25402"},{"key":"S0022215119001002_ref6","first-page":"CD008234","article-title":"Intratympanic gentamicin for M\u00e9ni\u00e8re's disease or syndrome","volume":"3","author":"Pullens","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"S0022215119001002_ref13","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26774"},{"key":"S0022215119001002_ref15","doi-asserted-by":"publisher","DOI":"10.1097\/01.wco.0000194373.08203.33"},{"key":"S0022215119001002_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215115002200"},{"key":"S0022215119001002_ref4","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2017.00258"},{"key":"S0022215119001002_ref2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001507"},{"key":"S0022215119001002_ref1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/6767216"},{"key":"S0022215119001002_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182956196"},{"key":"S0022215119001002_ref5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181bacf85"},{"key":"S0022215119001002_ref9","doi-asserted-by":"publisher","DOI":"10.1080\/00016480701663433"},{"key":"S0022215119001002_ref14","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2011.7.4.184"},{"key":"S0022215119001002_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2011.12.014"},{"key":"S0022215119001002_ref10","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2008.170878"}],"container-title":["The Journal of Laryngology & Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215119001002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,7]],"date-time":"2019-10-07T07:45:24Z","timestamp":1570434324000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215119001002\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,16]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["S0022215119001002"],"URL":"https:\/\/doi.org\/10.1017\/s0022215119001002","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,16]]}}}