{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T21:20:52Z","timestamp":1768252852589,"version":"3.49.0"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T00:00:00Z","timestamp":1598313600000},"content-version":"unspecified","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2020,8]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.<\/jats:p><\/jats:sec>Methods<\/jats:title>A prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.<\/jats:p><\/jats:sec>Results<\/jats:title>The mean age was 66.5 \u00b1 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 \u00b1 22.4 years (p<\/jats:italic> = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p<\/jats:italic> = 0.05).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Epistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. This may serve as a useful additional criterion for screening patients.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215120001863","type":"journal-article","created":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T03:44:20Z","timestamp":1598327060000},"page":"717-720","source":"Crossref","is-referenced-by-count":7,"title":["Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status \u2013 a prospective study"],"prefix":"10.1017","volume":"134","author":[{"given":"MH","family":"Hussain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Mair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Rea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,8,25]]},"reference":[{"key":"S0022215120001863_ref7","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24679"},{"key":"S0022215120001863_ref2","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin20.116"},{"key":"S0022215120001863_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000004351"},{"key":"S0022215120001863_ref5","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00404-18"},{"key":"S0022215120001863_ref11","unstructured":"11 ENT UK. 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