{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T09:29:42Z","timestamp":1691573382859},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"unspecified","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2021,1]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>This study aimed to evaluate the outcome of granular myringitis treatment of 1 per cent diluted vinegar ear drops or 1 per cent chloramphenicol ear drops and to assess the side effects of 1 per cent diluted vinegar.<\/jats:p><\/jats:sec>Method<\/jats:title>Twenty-four patients aged over 18 years and diagnosed with granular myringitis grade I or II within 90 days of symptom onset were included. Patients were equally randomised into either the 1 per cent diluted vinegar group or the 1 per cent chloramphenicol group. Outcome of treatment and side effects were compared between groups. The main outcome measure was completely epithelialised tympanic membrane at the eight-week period.<\/jats:p><\/jats:sec>Results<\/jats:title>Eleven of 12 patients treated with 1 per cent diluted vinegar had complete recovery. In the 1 per cent chloramphenicol group, 8 of 12 patients recovered. The difference between groups was not statistically significant (p<\/jats:italic> = 0.156). The observed side effects of diluted vinegar included dizziness and mild external auditory canal irritation.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>One per cent diluted vinegar is an interesting option for granular myringitis. Other comparative advantages of 1 per cent diluted vinegar include its low price and no induction of antimicrobial resistance.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215120002716","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T07:16:26Z","timestamp":1611558986000},"page":"33-38","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of diluted vinegar in treating granular myringitis: a randomised controlled trial"],"prefix":"10.1017","volume":"135","author":[{"given":"S","family":"Prakairungthong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Ungchoomchoke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Limviriyakul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Suvarnsit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Atipas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Thongyai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"key":"S0022215120002716_ref2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812470433"},{"key":"S0022215120002716_ref7","doi-asserted-by":"crossref","first-page":"273","DOI":"10.4103\/ijps.IJPS_245_16","article-title":"Acetic acid dressings: finding the Holy Grail for infected wound management","volume":"50","author":"Agrawal","year":"2017","journal-title":"Indian J Plast Surg"},{"key":"S0022215120002716_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joto.2018.11.003"},{"key":"S0022215120002716_ref13","first-page":"3","article-title":"Vinegar in chronic otitis externa and myringitis","volume":"16","author":"Taneja","year":"2010","journal-title":"Ind J Otol"},{"key":"S0022215120002716_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27179"},{"key":"S0022215120002716_ref9","doi-asserted-by":"publisher","DOI":"10.1111\/1750-3841.12434"},{"key":"S0022215120002716_ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2010.02118.x"},{"key":"S0022215120002716_ref10","doi-asserted-by":"publisher","DOI":"10.1086\/501694"},{"key":"S0022215120002716_ref3","doi-asserted-by":"publisher","DOI":"10.18203\/issn.2454-5929.ijohns20150900"},{"key":"S0022215120002716_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(00)00427-4"},{"key":"S0022215120002716_ref6","doi-asserted-by":"publisher","DOI":"10.1258\/0022215021910474"},{"key":"S0022215120002716_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000235379.72278.ed"},{"key":"S0022215120002716_ref12","first-page":"462","article-title":"Granular myringitis: is it a surgical problem","volume":"21","author":"El-Seifi","year":"2000","journal-title":"Am J Otol"}],"container-title":["The Journal of Laryngology & Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215120002716","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T07:34:22Z","timestamp":1623396862000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215120002716\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S0022215120002716"],"URL":"https:\/\/doi.org\/10.1017\/s0022215120002716","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}