{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:47:52Z","timestamp":1787741272753,"version":"build-2784847793"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S002221512100164X_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>Ventilation of the middle ear and mastoid air cells is believed to play an important role in the pathogenesis of chronic ear disease. Traditionally, ventilation is assessed by computed tomography. However, this exposes patients to cumulative radiation injury. In cases with a perforation in the tympanic membrane, tympanometry potentially presents a non-invasive alternative to measure the ventilated middle<jats:italic>-<\/jats:italic>ear and mastoid air cell volume. This study hypothesised that total tympanometry volume correlates with ventilated middle<jats:italic>-<\/jats:italic>ear and mastoid air cell volume.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512100164X_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>Total tympanometry volume was compared with ventilated middle<jats:italic>-<\/jats:italic>ear and mastoid air cell volume on computed tomography scans in 20 tympanic membrane perforations.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512100164X_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>There was a high correlation between tympanometry and computed tomography volumes (<jats:italic>r<\/jats:italic> = 0.78; <jats:italic>p<\/jats:italic> &lt; 0.001). A tympanometry volume more than 2 ml predicted good ventilation on computed tomography.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512100164X_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>These results may help reduce the need for pre-operative computed tomography in uncomplicated cases with tympanic membrane perforations.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s002221512100164x","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T05:17:51Z","timestamp":1625462271000},"page":"718-722","source":"Crossref","is-referenced-by-count":2,"title":["Correlation between tympanometry volume and three-dimensional computed tomography mastoid volumetry in tympanoplasty candidates"],"prefix":"10.1017","volume":"135","author":[{"given":"L","family":"Epprecht","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Qingsong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Stenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Hashimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Linder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,7,5]]},"reference":[{"key":"S002221512100164X_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.02.015"},{"key":"S002221512100164X_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2016.02.008"},{"key":"S002221512100164X_ref7","first-page":"46","article-title":"Volume measurement of middle ear and mastoid air cell system with impedance audiometry on patients with eardrum perforations","volume":"4","author":"Lindeman","year":"1982","journal-title":"Am J Otol"},{"key":"S002221512100164X_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002039"},{"key":"S002221512100164X_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2015.12.005"},{"key":"S002221512100164X_ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1984.00800310005002"},{"key":"S002221512100164X_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28107"},{"key":"S002221512100164X_ref5","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2013.311"},{"key":"S002221512100164X_ref6","volume-title":"Instrumentation for Audiology and Hearing Science: Theory and Practice","author":"Silman","year":"2011"},{"key":"S002221512100164X_ref1","unstructured":"1 Lalwani, A. CURRENT Diagnosis and Treatment in Otolaryngology\u2013Head and Neck Surgery, 2nd edn. New York: McGraw-Hill, 2008"},{"key":"S002221512100164X_ref12","doi-asserted-by":"publisher","DOI":"10.1177\/000348949710600107"},{"key":"S002221512100164X_ref10","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181dd13e2"},{"key":"S002221512100164X_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001249"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221512100164X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T09:31:39Z","timestamp":1627983099000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221512100164X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,5]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S002221512100164X"],"URL":"https:\/\/doi.org\/10.1017\/s002221512100164x","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,5]]}}}