{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T12:50:08Z","timestamp":1752670208042},"reference-count":31,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T00:00:00Z","timestamp":1629676800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215121001985_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>This study evaluated the post-operative indications for sinonasal topical steroid treatment using a corticosteroid (steroid)-eluting, sinus-bioabsorbable device and its effects in patients with eosinophilic chronic rhinosinusitis.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121001985_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>Post-operative courses were investigated in two groups: group A with patients who underwent sinonasal topical steroid treatment, and group B with control patients who did not.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121001985_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Group A was significantly younger than group B (<jats:italic>p<\/jats:italic> &lt; 0.01), and the pre-operative computed tomography score was significantly higher in group A than in group B (<jats:italic>p<\/jats:italic> &lt; 0.05). In the post-operative stage, the nasal symptoms questionnaire component of olfactory loss and the post-operative endoscopic appearance score were significantly worse in group A than in group B (<jats:italic>p<\/jats:italic> &lt; 0.01).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121001985_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>These data suggest that younger age, more severe rhinosinusitis and post-operative olfactory loss led to the need for sinonasal topical steroid treatment to prevent relapsing inflammation after functional endoscopic sinus surgery in patients with eosinophilic chronic rhinosinusitis.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215121001985","type":"journal-article","created":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T05:57:48Z","timestamp":1629698268000},"page":"858-863","source":"Crossref","is-referenced-by-count":5,"title":["Therapeutic indications for sinonasal topical steroid treatment and its effects on 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