{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:53:47Z","timestamp":1787626427433,"version":"build-2736575974"},"reference-count":66,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T00:00:00Z","timestamp":1627257600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215121002036_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>Parotid incidentalomas on fluorodeoxyglucose positron emission tomography\/computed tomography imaging are rare. A systematic review was performed to assess their aetiology and association with scanning indication, and to develop an evidence-based algorithm for their management.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002036_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A literature search was performed on 25 August 2020 using the keywords \u2018incidentaloma\u2019, \u2018incidental finding\u2019, \u2018parotid\u2019, \u2018parotid gland\u2019, \u2018salivary gland\u2019 and \u2018head and neck\u2019. Articles were reviewed by two authors before their inclusion.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002036_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Forty articles were included, totalling 558 incidentalomas. The mean incidence was 0.74 per cent. Lung cancer was the most common imaging indication. The most common aetiologies were cystadenolymphoma, pleomorphic salivary adenoma and metastases. Only cystadenolymphoma (<jats:italic>p<\/jats:italic>= 0.015) and pleomorphic salivary adenoma (<jats:italic>p<\/jats:italic>= 0.011) were significantly associated with a primary malignancy (lung). The most common further investigations were aspiration cytology, ultrasound imaging and core biopsy, usually prior to parotidectomy.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002036_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>If appropriate, parotid incidentalomas should be followed up with flexible endoscopy, skin examinations, and head and neck examinations. Ultrasound-guided core biopsy provides higher accuracy, avoiding repeat sampling and excision biopsy.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215121002036","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T11:14:08Z","timestamp":1627298048000},"page":"765-769","source":"Crossref","is-referenced-by-count":9,"title":["Parotid incidentalomas: a systematic 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