{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T15:07:36Z","timestamp":1748099256654,"version":"3.40.5"},"reference-count":43,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215121002693_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>Adenotonsillectomy is a recognised treatment for paediatric obstructive sleep apnoea. Recent literature highlights the need to assess outcomes in the extremely obese subpopulation. This study reviewed the efficacy of adenotonsillectomy performed in patients with extreme obesity.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002693_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>A retrospective analysis of attendees at a tertiary paediatric obesity clinic was performed, identifying patients with a body mass index <jats:italic>z<\/jats:italic>-score equal to or more than three who had undergone adenotonsillectomy for obstructive sleep apnoea. Electronic patient records, including respiratory polygraphy, were analysed.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002693_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Nine patients met the study criteria. All required nocturnal non-invasive ventilation pre-operatively. Mean age at referral was 6.9 years, and average age of non-invasive ventilation commencement was 7.8 years. Post-operatively, 8 patients (89 per cent) required non-invasive ventilation with evidence of post-operative obstructive sleep apnoea.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002693_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>In extreme obesity, adenotonsillectomy does not prevent the need for non-invasive ventilation. Management of this patient group requires treatment of obesity alongside potential surgical intervention. Poor efficacy in treating obstructive sleep apnoea may influence the decision to proceed with adenotonsillectomy.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215121002693","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T04:31:39Z","timestamp":1633062699000},"page":"1071-1076","source":"Crossref","is-referenced-by-count":2,"title":["Adenotonsillectomy for the treatment of obstructive sleep apnoea in extreme paediatric obesity"],"prefix":"10.1017","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6971-4210","authenticated-orcid":false,"given":"N","family":"Vakharia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Murkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Bajaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,10,1]]},"reference":[{"key":"S0022215121002693_ref8","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/148.2.462"},{"key":"S0022215121002693_ref14","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2017.3127"},{"key":"S0022215121002693_ref6","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2329C"},{"key":"S0022215121002693_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.02.033"},{"key":"S0022215121002693_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2016.09.026"},{"key":"S0022215121002693_ref17","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2329C"},{"key":"S0022215121002693_ref24","unstructured":"24 Working Party on Sleep Physiology and Respiratory Control Disorders in Childhood. Standards for Services for Children with Disorders of Sleep Physiology 2009. In: https:\/\/www.rcpch.ac.uk\/Research\/ce\/Guidelines-frontpage\/Guideline-Appraisals-by-Organisation\/RCPCH-Working-Party [19 May 2022]"},{"key":"S0022215121002693_ref39","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28663"},{"key":"S0022215121002693_ref20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c1918"},{"key":"S0022215121002693_ref1","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1016\/S0140-6736(17)32129-3","article-title":"Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128\u22c59 million children, adolescents, and adults","volume":"390","author":"Bentham","year":"2017","journal-title":"Lancet"},{"key":"S0022215121002693_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.02.024"},{"key":"S0022215121002693_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318093edd7"},{"key":"S0022215121002693_ref2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00689.2009"},{"key":"S0022215121002693_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.01.025"},{"key":"S0022215121002693_ref25","first-page":"224","article-title":"Update on paediatric obstructive sleep apnoea","volume":"8","author":"Dehlink","year":"2016","journal-title":"J Thorac Dis"},{"key":"S0022215121002693_ref41","first-page":"PA549","article-title":"Comparison of oxygen desaturation index and apnoea-hypopnoea index for categorising OSA in children","volume":"52","author":"Dos Santos","year":"2018","journal-title":"Eur Respir J"},{"key":"S0022215121002693_ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.04.031"},{"key":"S0022215121002693_ref30","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2008.673"},{"key":"S0022215121002693_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.05.008"},{"key":"S0022215121002693_ref36","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-017-0190-6"},{"key":"S0022215121002693_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.12.038"},{"key":"S0022215121002693_ref22","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.5_Pt_1.1231"},{"key":"S0022215121002693_ref3","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182a5cfb3"},{"key":"S0022215121002693_ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2016.06.018"},{"key":"S0022215121002693_ref34","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.06.016"},{"key":"S0022215121002693_ref21","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.2.405"},{"key":"S0022215121002693_ref4","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28335"},{"key":"S0022215121002693_ref10","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200708-138MG"},{"key":"S0022215121002693_ref37","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2020.12.028"},{"key":"S0022215121002693_ref33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1991.tb01050.x"},{"key":"S0022215121002693_ref13","first-page":"CD011165","article-title":"Tonsillectomy or adenotonsillectomy versus non-surgical management for obstructive sleep-disordered breathing in children","volume":"2015","author":"Venekamp","journal-title":"Cochrane Database Syst Rev"},{"key":"S0022215121002693_ref40","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13635"},{"key":"S0022215121002693_ref32","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27623"},{"key":"S0022215121002693_ref15","doi-asserted-by":"publisher","DOI":"10.1177\/0194599819829415"},{"key":"S0022215121002693_ref27","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.10.1123"},{"key":"S0022215121002693_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2013.05.011"},{"key":"S0022215121002693_ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2008.09.027"},{"key":"S0022215121002693_ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2014.02.003"},{"key":"S0022215121002693_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.08.008"},{"key":"S0022215121002693_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26830"},{"key":"S0022215121002693_ref23","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2003.007203"},{"key":"S0022215121002693_ref42","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-4262-4"},{"key":"S0022215121002693_ref43","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.07.043497"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215121002693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T13:52:52Z","timestamp":1666187572000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215121002693\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,1]]},"references-count":43,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S0022215121002693"],"URL":"https:\/\/doi.org\/10.1017\/s0022215121002693","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"type":"print","value":"0022-2151"},{"type":"electronic","value":"1748-5460"}],"subject":[],"published":{"date-parts":[[2021,10,1]]}}}