{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T09:46:06Z","timestamp":1694598366897},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T00:00:00Z","timestamp":1633910400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215121002838_sec_a1\"><jats:title>Background<\/jats:title><jats:p>Decades of clinical observation have led our subspecialty team to suspect that negative nasopharyngeal pressure is associated with attic retraction pocket formation. Furthermore, LaPlace's law, which states that the pressure within a sphere varies with the inverse of the radius, provides the dynamic explanation for why the attic area of the tympanic membrane tends to retract more frequently than the pars tensa.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002838_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>The attic retraction pockets of 154 patients were classified into grades of severity (grades I\u2013V). Impedance audiometry of middle-ear pressure was measured in the resting state, and after sniffing, swallowing and the Valsalva manoeuvre.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002838_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Negative nasopharyngeal pressure (sniffing) caused a diminution of middle-ear pressure of \u22125 daPa on average in normal ears, and of \u221224 daPa to \u221245 daPa for tympanic membranes with attic retraction pockets of grade I to grade V.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121002838_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>Attic retraction pockets are associated with greater collapse of middle-ear volume when negative pressure is created in the nasopharynx. LaPlace's law, and the composition of the pars flaccida, suggests an explanation for why the attic region retracts more than the pars tensa.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215121002838","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T10:32:25Z","timestamp":1633948345000},"page":"1100-1104","source":"Crossref","is-referenced-by-count":1,"title":["Unmitigated negative nasopharyngeal pressure is associated with attic retraction pocket formation: LaPlace's law in action"],"prefix":"10.1017","volume":"135","author":[{"given":"Nilesh H","family":"Mahajan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Vijayendra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinay Kumar","family":"Vijayendra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Redleaf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,10,11]]},"reference":[{"key":"S0022215121002838_ref2","doi-asserted-by":"publisher","DOI":"10.3109\/00016489609137716"},{"key":"S0022215121002838_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24165"},{"key":"S0022215121002838_ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1997.01900060026004"},{"key":"S0022215121002838_ref9","doi-asserted-by":"publisher","DOI":"10.3109\/00016487809124763"},{"key":"S0022215121002838_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-15363-2_2"},{"key":"S0022215121002838_ref3","doi-asserted-by":"publisher","DOI":"10.1177\/019459988409200313"},{"key":"S0022215121002838_ref6","unstructured":"6 Law of LaPlace (experiment). In: https:\/\/youtu.be\/_btWTwDVRj8 [7 October 2021]"},{"key":"S0022215121002838_ref5","first-page":"790","volume-title":"Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems","author":"Thiriet","year":"2013"},{"key":"S0022215121002838_ref1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28368"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215121002838","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T14:07:00Z","timestamp":1637935620000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215121002838\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,11]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["S0022215121002838"],"URL":"https:\/\/doi.org\/10.1017\/s0022215121002838","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,11]]}}}