{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T19:01:18Z","timestamp":1793905278632,"version":"4.8.0"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:00:00Z","timestamp":1651795200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2022,10]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>The presentation of unilateral nasal polyps traditionally necessitates histological evaluation for a neoplasm. This study sought to determine the rates of significant pathology in patients presenting with benign-appearing unilateral nasal polyps, to inform practice.<\/jats:p><\/jats:sec>Method<\/jats:title>All patients who underwent nasal polypectomy for benign-appearing unilateral nasal polyps over a 13-year period were included.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 77 patients were included. On histology, 60 cases (77.9 per cent) were found to be inflammatory polyps. Thirteen cases were neoplastic, of which 11 (14.3 per cent) were benign and 2 (2.6 per cent) were malignant neoplasms. The following significant pathologies were found: Schneiderian papillomas, in 10 cases (13.0 per cent); neurofibroma, in 1 case (1.3 per cent); adenoid cystic carcinoma, in 1 case (1.3 per cent); and malignant melanoma, in 1 case (1.3 per cent).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Our data support routine histological assessment for all unilateral nasal polyps. Malignancy is rare (2.6 per cent) in patients presenting with benign-appearing unilateral nasal polyps. In elderly, unfit patients with minimal symptoms, initial conservative management may be reasonable.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215121003480","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T03:34:05Z","timestamp":1651808045000},"page":"998-1001","source":"Crossref","is-referenced-by-count":4,"title":["The incidence of significant pathology in patients presenting with benign-appearing unilateral nasal polyps"],"prefix":"10.1017","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6205-806X","authenticated-orcid":false,"given":"O","family":"Edafe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Weight","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Morsy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Mirza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,5,6]]},"reference":[{"key":"S0022215121003480_ref13","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3182085598"},{"key":"S0022215121003480_ref1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S2379"},{"key":"S0022215121003480_ref12","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1007\/s00405-011-1534-x","article-title":"Is routine histopathological analysis of nasal polyposis specimens necessary","volume":"268","author":"Yaman","year":"2011","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"S0022215121003480_ref7","first-page":"372","article-title":"Clinico-pathological profile of sinonasal masses: a study from a tertiary care hospital of India","volume":"31","author":"Lathi","year":"2011","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"S0022215121003480_ref6","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215115000213"},{"key":"S0022215121003480_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12415"},{"key":"S0022215121003480_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2007.07.001"},{"key":"S0022215121003480_ref4","doi-asserted-by":"crossref","first-page":"16","DOI":"10.4103\/nmj.NMJ_128_19","article-title":"Unilateral sinonasal masses: review of clinical presentation and outcome in Ahmadu Bello University Teaching Hospital, Zaria, Nigeria","volume":"61","author":"Shuaibu","year":"2020","journal-title":"Niger Med J"},{"key":"S0022215121003480_ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-011-0288-5"},{"key":"S0022215121003480_ref2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3238297"},{"key":"S0022215121003480_ref8","doi-asserted-by":"publisher","DOI":"10.1258\/0022215001904086"},{"key":"S0022215121003480_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21526"},{"key":"S0022215121003480_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.10.002"},{"key":"S0022215121003480_ref3","first-page":"139","article-title":"Single-sided sinonasal mass: a retrospective study","volume":"5","author":"Belli","year":"2018","journal-title":"North Clin Istanb"}],"container-title":["The Journal of Laryngology & Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215121003480","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T09:46:56Z","timestamp":1664272016000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215121003480\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,6]]},"references-count":14,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0022215121003480"],"URL":"https:\/\/doi.org\/10.1017\/s0022215121003480","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,6]]}}}