{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T11:28:40Z","timestamp":1767007720096},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T00:00:00Z","timestamp":1637798400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215121003716_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>To determine the outcomes of tympanoplasty surgery using porcine-derived small intestinal submucosa.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121003716_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>A retrospective audit was conducted in a hospital setting. Thirty-five adult and paediatric patients who received a small intestinal submucosa graft as part of tympanoplasty surgery were retrospectively reviewed. Patients underwent either simple tympanoplasty (<jats:italic>n<\/jats:italic> = 26) or complex tympanoplasty as part of a concurrent otological procedure such as atticotomy and mastoidectomy. The main outcome measures were rate of tympanic membrane closure and change in four-frequency mean air\u2013bone gap.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121003716_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Thirty-one patients had a follow-up period of longer than two months. Closure was obtained in 22 patients (71 per cent). The mean air\u2013bone gap improved from 20.7 to 12.3 dB HL in the simple tympanoplasty group and from 22.3 to 12 dB HL in the complex tympanoplasty group.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121003716_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>Tympanoplasty surgery with small intestinal submucosa is a viable option for patients where autologous graft is not available or in order to minimise donor site morbidity.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215121003716","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T08:05:03Z","timestamp":1637827503000},"page":"304-308","source":"Crossref","is-referenced-by-count":4,"title":["Outcomes following tympanoplasty surgery using porcine-derived small intestinal submucosa"],"prefix":"10.1017","volume":"136","author":[{"given":"K","family":"Pollaers","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Bumbak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Kuthubutheen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,11,25]]},"reference":[{"key":"S0022215121003716_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2015.04.037"},{"key":"S0022215121003716_ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200303000-00007"},{"key":"S0022215121003716_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001792"},{"key":"S0022215121003716_ref5","doi-asserted-by":"publisher","DOI":"10.1177\/019459988910100601"},{"key":"S0022215121003716_ref7","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000190462.50755.f2"},{"key":"S0022215121003716_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199712001-00002"},{"key":"S0022215121003716_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26568"},{"key":"S0022215121003716_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2017.03.017"},{"key":"S0022215121003716_ref1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001099"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215121003716","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T09:12:19Z","timestamp":1651223539000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215121003716\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,25]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S0022215121003716"],"URL":"https:\/\/doi.org\/10.1017\/s0022215121003716","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,25]]}}}