{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:03:47Z","timestamp":1792728227624,"version":"4.5.0"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T00:00:00Z","timestamp":1637884800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215121003947_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>The role of high-resolution computed tomography scans in otosclerosis remains uncertain. There is a debate over the relationship between radiological and audiometric findings among patients.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121003947_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>Pre-operative audiometry and high-resolution computed tomography findings from 40 ears with surgically confirmed otosclerosis were compared. High-resolution computed tomography scan data regarding the characteristics of the disease foci, the endosteal extension and the occurrence of internal auditory canal diverticula were obtained. The influence of each radiological variable on the simple pure tone average, the high-frequency pure tone average and the bone-conduction pure tone average were investigated.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121003947_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Cases with endosteal extension (<jats:italic>p<\/jats:italic> = 0.047) and a higher number of affected sites within the otic capsule had a worse bone-conduction pure tone average, although it was only significant for the latter (<jats:italic>p<\/jats:italic> = 0.006). Those without concomitant retrofenestral disease (<jats:italic>p<\/jats:italic> = 0.019) had better simple pure tone average.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121003947_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>The number of sites of involvement and concomitant retrofenestral disease seem to significantly impact audiometric findings in otosclerosis.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215121003947","type":"journal-article","created":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T07:31:34Z","timestamp":1637911894000},"page":"68-75","source":"Crossref","is-referenced-by-count":2,"title":["Radiological parameters and audiometric findings in otosclerosis: is there any relationship?"],"prefix":"10.1017","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3443-3640","authenticated-orcid":false,"given":"L R L","family":"Mangia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G L O","family":"Salvador","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N T","family":"Amadeu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G A","family":"Marroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Coifman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Hamerschmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,11,26]]},"reference":[{"key":"S0022215121003947_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.11.030"},{"key":"S0022215121003947_ref19","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200103000-00023"},{"key":"S0022215121003947_ref23","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000171052.34196.ef"},{"key":"S0022215121003947_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2017.11.005"},{"key":"S0022215121003947_ref8","first-page":"297","article-title":"The enzymatic mechanism of the otospongiotic disease and NaF action on the enzymatic balance","volume":"3","author":"Causse","year":"1982","journal-title":"Am J Otol"},{"key":"S0022215121003947_ref13","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1080\/000164801300043505","article-title":"Sensorineural hearing loss and otosclerosis: a clinical and radiologic survey of 437 cases","volume":"121","author":"Shin","year":"2001","journal-title":"Acta Otolaryngol"},{"key":"S0022215121003947_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2009.04.010"},{"key":"S0022215121003947_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/0196-0709(89)90086-0"},{"key":"S0022215121003947_ref6","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.151.3.6718730"},{"key":"S0022215121003947_ref15","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1288\/00005537-198306000-00003","article-title":"Otosclerosis: relationship of spiral ligament hyalinization to sensorineural hearing loss","volume":"93","author":"Parahy","year":"1983","journal-title":"Laryngoscope"},{"key":"S0022215121003947_ref17","doi-asserted-by":"publisher","DOI":"10.1177\/019459988108900239"},{"key":"S0022215121003947_ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-009-0967-y"},{"key":"S0022215121003947_ref10","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31826352ad"},{"key":"S0022215121003947_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2004.01.006"},{"key":"S0022215121003947_ref21","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2018.1521526"},{"key":"S0022215121003947_ref24","doi-asserted-by":"publisher","DOI":"10.3109\/00313028409067908"},{"key":"S0022215121003947_ref5","first-page":"44","volume-title":"Auditory Diagnosis: Principles and Applications","author":"Silman","year":"1997"},{"key":"S0022215121003947_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)30815-X"},{"key":"S0022215121003947_ref16","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198511000-00003"},{"key":"S0022215121003947_ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4446-8"},{"key":"S0022215121003947_ref22","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5613"},{"key":"S0022215121003947_ref1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1558"},{"key":"S0022215121003947_ref11","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2010.549841"},{"key":"S0022215121003947_ref12","doi-asserted-by":"publisher","DOI":"10.1177\/000348940511400910"}],"container-title":["The Journal of Laryngology &amp; 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