{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:39:02Z","timestamp":1761824342090,"version":"3.40.5"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:00:00Z","timestamp":1642032000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215121004576_sec_a1\"><jats:title>Background<\/jats:title><jats:p>Cholesteatoma often presents with persistent otorrhoea, conductive hearing loss or vestibular dysfunction. Rarely, cholesteatoma can cause dysgeusia if the lesion invades into the chorda tympani nerve. This paper presents an individual with cholesteatoma whose dysgeusia resolved following a mastoidectomy in which the chorda tympani was sacrificed. The current literature was reviewed for explanations behind this phenomenon.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121004576_sec_a2\"><jats:title>Case report<\/jats:title><jats:p>A previously fit 57-year-old man presented with a 3-month history of persistent otorrhoea and the complaint of a metallic taste in the mouth, and was diagnosed with cholesteatoma. The patient underwent radical mastoidectomy and the chorda tympani nerve was sacrificed. On post-operative review, he reported complete resolution of dysgeusia.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215121004576_sec_a3\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>The sense of taste is mediated by a complex neural network. It is possible that once the diseased chorda tympani is transected, compensation arises from other parts of the network. Sectioning of the chorda tympani could lead to a beneficial outcome in selected patients.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215121004576","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T01:08:22Z","timestamp":1642036102000},"page":"373-374","source":"Crossref","is-referenced-by-count":1,"title":["Sacrifice of the chorda tympani nerve during middle-ear surgery can lead to resolution of dysgeusia"],"prefix":"10.1017","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4242-0391","authenticated-orcid":false,"given":"K L","family":"Lau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Tustin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Stafford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2022,1,13]]},"reference":[{"key":"S0022215121004576_ref2","doi-asserted-by":"publisher","DOI":"10.1308\/147870807X160425"},{"key":"S0022215121004576_ref10","doi-asserted-by":"publisher","DOI":"10.1179\/cim.2007.8.4.203"},{"key":"S0022215121004576_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.12.022"},{"key":"S0022215121004576_ref8","doi-asserted-by":"publisher","DOI":"10.1258\/0022215053561657"},{"key":"S0022215121004576_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200104000-00029"},{"key":"S0022215121004576_ref5","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199401000-00006"},{"key":"S0022215121004576_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-004-0854-5"},{"key":"S0022215121004576_ref7","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-19-08607.2002"},{"key":"S0022215121004576_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215111002623"},{"key":"S0022215121004576_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2005.11.020"},{"key":"S0022215121004576_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/23.6.661"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215121004576","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T09:13:46Z","timestamp":1651223626000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215121004576\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,13]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S0022215121004576"],"URL":"https:\/\/doi.org\/10.1017\/s0022215121004576","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"type":"print","value":"0022-2151"},{"type":"electronic","value":"1748-5460"}],"subject":[],"published":{"date-parts":[[2022,1,13]]}}}