{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:52:59Z","timestamp":1747173179767,"version":"3.40.5"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215122000925_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>This study evaluated the olfactory, sinonasal and mucociliary functions of patients with post-coronavirus disease 2019 long-term persistent olfactory dysfunction.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215122000925_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>Three groups of 30 patients each were formed: patients with a history of coronavirus disease 2019 infection with self-reported, persistent, sudden-onset olfactory dysfunction (group 1), patients with a history of coronavirus disease 2019 infection without any self-reported olfactory dysfunction (group 2) and healthy controls with no history of coronavirus disease 2019 infection (group 3). Saccharin time, Sniffin\u2019 Sticks, Turkish Nasal Obstruction Symptom Evaluation and Sino-Nasal Outcome Test 22 scores were compared.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215122000925_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Turkish Nasal Obstruction Symptom Evaluation scores were similar between groups (<jats:italic>p =<\/jats:italic> 0.252). Sino-Nasal Outcome Test-22 scores were higher in group 1 than groups 2 and 3 (<jats:italic>p &lt;<\/jats:italic> 0.01 and <jats:italic>p &lt;<\/jats:italic> 0.001, respectively). Saccharin time was significantly longer in group 1 than groups 2 and 3 (<jats:italic>p &lt;<\/jats:italic> 0.05 and <jats:italic>p &lt;<\/jats:italic> 0.01, respectively). Group 1 had lower olfactory scores than groups 2 and 3 (<jats:italic>p &lt;<\/jats:italic> 0.001 and <jats:italic>p &lt;<\/jats:italic> 0.001, respectively).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215122000925_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>Mucociliary clearance time was significantly prolonged in patients with post-coronavirus disease 2019 persistent olfactory dysfunction. Coronavirus disease 2019 infection was likely to cause asymptomatic olfactory dysfunction.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215122000925","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T01:15:29Z","timestamp":1649207729000},"page":"742-746","source":"Crossref","is-referenced-by-count":0,"title":["The residual effect of coronovirus disease 2019 on olfactory acuity and mucociliary clearance time: a cross-sectional, controlled study"],"prefix":"10.1017","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3354-2212","authenticated-orcid":false,"given":"S","family":"Kandemir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8813-0357","authenticated-orcid":false,"given":"A E","family":"Pamuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2022,4,6]]},"reference":[{"doi-asserted-by":"publisher","key":"S0022215122000925_ref1","DOI":"10.1007\/s00405-020-05965-1"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref6","DOI":"10.5152\/B-ENT.2020.20028"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref8","DOI":"10.1002\/alr.22688"},{"key":"S0022215122000925_ref14","first-page":"223","article-title":"Factors associated with inaccurate self-reporting of olfactory dysfunction in older US adults","volume":"42","author":"Adams","year":"2017","journal-title":"Chemical senses"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref21","DOI":"10.3390\/molecules25102271"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref25","DOI":"10.1126\/science.286.5440.711"},{"key":"S0022215122000925_ref15","first-page":"S1808","article-title":"Pathophysiological relationship between Covid-19 and olfactory dysfunction: a systematic review","volume":"25","author":"Las Casas Lima","year":"2021","journal-title":"Braz J Otorhinolaryngol"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref13","DOI":"10.1016\/j.amjoto.2021.103076"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref22","DOI":"10.1021\/acschemneuro.0c00201"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref9","DOI":"10.3906\/sag-1509-81"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref12","DOI":"10.1016\/j.amjoto.2021.103014"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref20","DOI":"10.1016\/j.amjoto.2020.102796"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref23","DOI":"10.1523\/JNEUROSCI.3261-17.2018"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref18","DOI":"10.1016\/j.bbi.2020.06.032"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref19","DOI":"10.1056\/NEJMc2001737"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref10","DOI":"10.1111\/coa.13332"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref4","DOI":"10.1111\/ene.14994"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref7","DOI":"10.1007\/s00405-020-06457-y"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref17","DOI":"10.1126\/sciadv.abc5801"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref16","DOI":"10.3390\/pharmaceutics10030116"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref3","DOI":"10.1001\/jama.2020.12603"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref5","DOI":"10.1007\/s00405-014-3118-z"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref24","DOI":"10.1056\/NEJM198502213120802"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref11","DOI":"10.1097\/00005537-200001000-00021"},{"doi-asserted-by":"publisher","key":"S0022215122000925_ref2","DOI":"10.1007\/s00405-021-06839-w"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215122000925","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T11:10:33Z","timestamp":1659525033000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215122000925\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,6]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S0022215122000925"],"URL":"https:\/\/doi.org\/10.1017\/s0022215122000925","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"type":"print","value":"0022-2151"},{"type":"electronic","value":"1748-5460"}],"subject":[],"published":{"date-parts":[[2022,4,6]]}}}