{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T12:24:55Z","timestamp":1773059095238,"version":"3.50.1"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:00:00Z","timestamp":1652140800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215122001141_sec_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Drains are used post-parotidectomy to reduce seroma and haematoma formation. Tissue-derived thrombin sealant can enable a drainless procedure, allowing for an earlier discharge, less discomfort and a more cost-efficient method. This study aimed to assess whether tissue sealant improves wound-related outcomes in parotidectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215122001141_sec_a2\">\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A systematic literature review was performed using a standardised published methodology and custom database search strategy. A fixed-effect meta-analysis of the combined complications was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215122001141_sec_a3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen studies were identified relating to parotidectomy procedures using tissue sealants, of which nine were included in the quantitative synthesis. Our analysis suggested a reduction in the complication rates, including haematoma and seroma, with drainless parotidectomy procedures involving tissue sealant use when compared with conventional procedures with post-operative drain use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215122001141_sec_a4\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Fibrin sealant in parotidectomy may be used to facilitate a drainless approach, expediting recovery and offering better comfort to patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215122001141","type":"journal-article","created":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T06:45:35Z","timestamp":1652165135000},"page":"168-181","source":"Crossref","is-referenced-by-count":0,"title":["The use of tissue sealant in parotidectomy: a systematic review and meta-analysis"],"prefix":"10.1017","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0082-3395","authenticated-orcid":false,"given":"D M","family":"Rojoa","sequence":"first","affiliation":[{"name":"Royal Oldham Hospital"},{"name":"University Hospitals of Leicester"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F J","family":"Raheman","sequence":"additional","affiliation":[{"name":"University Hospitals of Leicester"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Wright","sequence":"additional","affiliation":[{"name":"Royal Oldham Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Royal Oldham Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"key":"S0022215122001141_ref24","first-page":"2025","article-title":"Drainless parotidectomies versus conventional parotidectomies: randomised control study on efficacy and safety","volume":"276","author":"Chua","year":"2019","journal-title":"Ann Acad Med"},{"key":"S0022215122001141_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000231785.96955.c8"},{"key":"S0022215122001141_ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-05903-1"},{"key":"S0022215122001141_ref1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12837"},{"key":"S0022215122001141_ref28","doi-asserted-by":"publisher","DOI":"10.1097\/00006199-200307000-00008"},{"key":"S0022215122001141_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2013.04.003"},{"key":"S0022215122001141_ref18","first-page":"19","article-title":"Biological glues based on fibrin for use in parotid tumour surgery","volume":"11","author":"Trujillo","year":"2009","journal-title":"Transfus Altern Transfus Med"},{"key":"S0022215122001141_ref7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.19163"},{"key":"S0022215122001141_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20999"},{"key":"S0022215122001141_ref22","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199606000-00022"},{"key":"S0022215122001141_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9448"},{"key":"S0022215122001141_ref2","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13339"},{"key":"S0022215122001141_ref17","first-page":"208","article-title":"Use of tissue sealant for day surgery parotidectomy","volume":"37","author":"Conboy","year":"2008","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"S0022215122001141_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2019.10.008"},{"key":"S0022215122001141_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02786-0"},{"key":"S0022215122001141_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.sdentj.2010.11.002"},{"key":"S0022215122001141_ref13","doi-asserted-by":"publisher","DOI":"10.14712\/18059694.2017.112"},{"key":"S0022215122001141_ref29","unstructured":"29 Gardner, L . Past national tariffs: documents and policies. In: https:\/\/www.england.nhs.uk\/publication\/past-national-tariffs-documents-and-policies\/ [8 May 2023]"},{"key":"S0022215122001141_ref9","first-page":"759","article-title":"The effect evaluation of suction drainage to prevent fistula after superficial parotidectomy","volume":"23","author":"Jiang","year":"2014","journal-title":"Shanghai Kou Qiang Yi Xue"},{"key":"S0022215122001141_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.06.208"},{"key":"S0022215122001141_ref16","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13386"},{"key":"S0022215122001141_ref21","doi-asserted-by":"publisher","DOI":"10.2310\/7070.2005.4032"},{"key":"S0022215122001141_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2015.08.353"},{"key":"S0022215122001141_ref11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.1536"},{"key":"S0022215122001141_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-019-05449-x"},{"key":"S0022215122001141_ref20","first-page":"S111","article-title":"Artiss\u00ae in parotid surgery: are suction drains still required? 55th Annual IHNS Meeting Report 2014","volume":"184","author":"Heffernan","year":"2015","journal-title":"Irish J Med Sci"},{"key":"S0022215122001141_ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-019-05540-3"},{"key":"S0022215122001141_ref14","first-page":"313","article-title":"Relevance of Choukroun's platelet-rich fibrin (PRF) and SMAS flap in primary reconstruction after superficial or subtotal parotidectomy in patients with focal pleiomorphic adenoma: a new technique","volume":"129","author":"Charrier","year":"2008","journal-title":"Rev Laryngol Otol Rhinol"},{"key":"S0022215122001141_ref3","first-page":"412","article-title":"Effects of dra\u0131ns on pain, comfort and anxiety in pat\u0131ents undergone surgery","volume":"6","author":"Findik","year":"2013","journal-title":"Int J Caring Sci"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215122001141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:38:50Z","timestamp":1773049130000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215122001141\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,10]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S0022215122001141"],"URL":"https:\/\/doi.org\/10.1017\/s0022215122001141","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,10]]}}}