{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T05:21:57Z","timestamp":1784524917610,"version":"3.55.0"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:00:00Z","timestamp":1654646400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215122001347_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>This study aimed to assess the clinical implications of delayed-acquisition post-gadolinium magnetic resonance imaging in identifying endolymphatic hydrops in M\u00e9ni\u00e8re's disease.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215122001347_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>This study was a systematic review using Medline and Embase and following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines with predetermined criteria, namely M\u00e9ni\u00e8re's disease, post-gadolinium magnetic resonance imaging and endolymphatic hydrops. The Quality Assessment of Diagnostic Accuracy Studies-2 tool was used to assess bias.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215122001347_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Eleven studies were included; they all used 3T magnetic resonance imaging, with three-dimensional fluid-attenuated inversion recovery being the most common sequence. Intravenous gadolinium administration was more widely used compared with the intratympanic route. As for the timing of acquisition, 4 hours post-administration was universally used for the IV gadolinium and 24 hours was used for the intratympanic gadolinium. Despite patient-selection associated bias, all studies reported adequate visualisation of the endolymphatic spaces.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215122001347_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>The use of delayed-acquisition magnetic resonance imaging is increasingly supported in visualising the endolymphatic spaces in M\u00e9ni\u00e8re's disease. Although the accessibility of 3T magnetic resonance imaging questions its wider applicability, it is a promising tool for the near future.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215122001347","type":"journal-article","created":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T10:53:44Z","timestamp":1654685624000},"page":"239-245","source":"Crossref","is-referenced-by-count":6,"title":["A systematic review on delayed acquisition of post-gadolinium magnetic resonance imaging in M\u00e9ni\u00e8re's disease: imaging of the endolymphatic spaces"],"prefix":"10.1017","volume":"137","author":[{"given":"A","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1637-1661","authenticated-orcid":false,"given":"G","family":"Kontorinis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,6,8]]},"reference":[{"key":"S0022215122001347_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2017.02.002"},{"key":"S0022215122001347_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31820e7614"},{"key":"S0022215122001347_ref17","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3856"},{"key":"S0022215122001347_ref19","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2010.534114"},{"key":"S0022215122001347_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2020.07.021"},{"key":"S0022215122001347_ref1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0194-5998(95)70102-8","article-title":"Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meni\u00e8re's disease. 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