{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:20:36Z","timestamp":1788438036166,"version":"build-2803163510"},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2023,5]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>The added value of hybrid positron emission tomography is increasingly recognised in head and neck cancer. However, its potential role in salivary gland carcinomas has been scarcely investigated.<\/jats:p><\/jats:sec>Methods<\/jats:title>A consecutive cohort of 45 salivary gland carcinoma patients who underwent pre-therapeutic hybrid positron emission tomography and surgical resection was reviewed. This study investigated whether maximum standardised uptake value correlated with tumour phenotype.<\/jats:p><\/jats:sec>Results<\/jats:title>Tumours of high-grade disease on histology (salivary duct carcinoma, carcinoma ex pleomorphic adenoma) had higher maximum standardised uptake value (Kruskal\u2013Wallis test, p<\/jats:italic> = 0.011) than low-grade tumours (adenoid cystic carcinoma and acinic cell carcinoma). Patients with pathologically confirmed node-positive disease had significantly higher maximum standardised uptake value of the primary tumour than patients with pathologically confirmed node-negative disease (Kruskal\u2013Wallis test, p<\/jats:italic> = 0.012).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Maximum standardised uptake value of the primary tumour may guide clinical decision-making in patients with salivary gland carcinomas, as a high maximum standardised uptake value is associated with high-grade tumour histology and the presence of lymph node metastases. Clinicians may consider more aggressive surgery for these patients.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215122001475","type":"journal-article","created":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T03:37:56Z","timestamp":1655869076000},"page":"551-555","source":"Crossref","is-referenced-by-count":5,"title":["Potential role of hybrid positron emission tomography in pre-operative assessment of primary salivary gland carcinomas"],"prefix":"10.1017","volume":"137","author":[{"given":"S","family":"Karimian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M W","family":"H\u00fcllner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N J","family":"Rupp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S 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