{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:53:07Z","timestamp":1780487587317,"version":"3.54.1"},"reference-count":41,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S002221512200175X_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>This study aimed to analyse the outcomes of surgery for pleomorphic adenoma of the parapharyngeal space in relation to the surgical approach.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512200175X_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>This was a single-centre retrospective data analysis conducted from January 2008 to December 2020 on all patients who underwent operation for pleomorphic adenoma originating from the parapharyngeal space.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512200175X_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Twenty-one patients with a mean age of 52.6 years were included. The transparotid-transcervical approach was the most common (52.4 per cent,<jats:italic>n =<\/jats:italic>11) surgical approach, followed by transoral robotic surgery (28.6 per cent,<jats:italic>n =<\/jats:italic>6) and conventional transoral surgery (19 per cent,<jats:italic>n =<\/jats:italic>4). Post-operative complications included nine cases of transient partial facial nerve palsy and two cases of Frey's syndrome after the transparotid-transcervical approach and 2 cases of transient trismus and 1 pharyngeal wound dehiscence in the conventional transoral approach group. Complete macroscopic excision was always achieved, and no recurrence occurred during follow up.<\/jats:p><\/jats:sec><jats:sec id=\"S002221512200175X_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>These three approaches can provide adequate tumour visualisation, a high rate of clear excisional margins and an acceptable morbidity.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s002221512200175x","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T07:21:09Z","timestamp":1659511269000},"page":"741-748","source":"Crossref","is-referenced-by-count":9,"title":["Surgical approaches for pleomorphic adenoma of the parapharyngeal space"],"prefix":"10.1017","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1354-9281","authenticated-orcid":false,"given":"F","family":"Al Zadjali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Chabrillac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Vergez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,8,3]]},"reference":[{"key":"S002221512200175X_ref24","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23739"},{"key":"S002221512200175X_ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-017-1099-0"},{"key":"S002221512200175X_ref18","first-page":"87","article-title":"Transoral resection of giant parapharyngeal space tumors via a combined surgical approach","volume":"31","author":"Markou","year":"2019","journal-title":"Iran J Otorhinolaryngol"},{"key":"S002221512200175X_ref4","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1016\/j.joms.2019.03.001","article-title":"Surgical treatment of primary parapharyngeal space tumors: a single-institution review of 28 cases","volume":"77","author":"Chen","year":"2019","journal-title":"J Oral Maxillofac Surg"},{"key":"S002221512200175X_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2018.01.008"},{"key":"S002221512200175X_ref34","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2014.04.005"},{"key":"S002221512200175X_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25929"},{"key":"S002221512200175X_ref37","doi-asserted-by":"publisher","DOI":"10.1016\/S0344-0338(11)80220-7"},{"key":"S002221512200175X_ref31","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-4891-x"},{"key":"S002221512200175X_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(50)90297-0"},{"key":"S002221512200175X_ref7","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/hed.25439","article-title":"Contemporary management of primary parapharyngeal space tumors","volume":"41","author":"L\u00f3pez","year":"2019","journal-title":"Head Neck"},{"key":"S002221512200175X_ref22","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215118001184"},{"key":"S002221512200175X_ref26","doi-asserted-by":"publisher","DOI":"10.1002\/rcs.2083"},{"key":"S002221512200175X_ref10","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25077"},{"key":"S002221512200175X_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.104581"},{"key":"S002221512200175X_ref12","first-page":"310","article-title":"Parapharyngeal space tumours: the efficiency of a transcervical approach without mandibulotomy through review of 44 cases","volume":"34","author":"Basaran","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"S002221512200175X_ref6","first-page":"10","article-title":"Surgical management of parapharyngeal space tumours: results of 10-year follow-up","volume":"29","author":"Bozza","year":"2009","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"S002221512200175X_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06718-4"},{"key":"S002221512200175X_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-012-0508-7"},{"key":"S002221512200175X_ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090210"},{"key":"S002221512200175X_ref2","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.6480"},{"key":"S002221512200175X_ref13","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25552"},{"key":"S002221512200175X_ref21","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.12.1215"},{"key":"S002221512200175X_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2010.06.005"},{"key":"S002221512200175X_ref41","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-020-08536-0"},{"key":"S002221512200175X_ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.09.003"},{"key":"S002221512200175X_ref33","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111001202"},{"key":"S002221512200175X_ref35","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880170209"},{"key":"S002221512200175X_ref36","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199601\/02)18:1<67::AID-HED9>3.0.CO;2-X"},{"key":"S002221512200175X_ref17","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1017\/S0022215107009875","article-title":"Standardised method of selecting surgical approaches to benign parapharyngeal space tumours, based on pre-operative images","volume":"122","author":"Kanzaki","year":"2008","journal-title":"J Laryngol Otol"},{"key":"S002221512200175X_ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2009.11.011"},{"key":"S002221512200175X_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2014.02.007"},{"key":"S002221512200175X_ref11","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.169.1.2843942"},{"key":"S002221512200175X_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/dc.21508"},{"key":"S002221512200175X_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1994.104.s63.1"},{"key":"S002221512200175X_ref38","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2017.00026"},{"key":"S002221512200175X_ref40","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.2005.00993.x"},{"key":"S002221512200175X_ref39","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10281"},{"key":"S002221512200175X_ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-009-0047-z"},{"key":"S002221512200175X_ref27","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20199"},{"key":"S002221512200175X_ref25","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23557"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221512200175X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,25]],"date-time":"2023-11-25T07:59:21Z","timestamp":1700899161000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221512200175X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,3]]},"references-count":41,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S002221512200175X"],"URL":"https:\/\/doi.org\/10.1017\/s002221512200175x","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,3]]}}}