{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T19:01:30Z","timestamp":1791658890889,"version":"4.3.4"},"reference-count":61,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:00:00Z","timestamp":1684281600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215123000877_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>This study aimed to evaluate the recovery of olfactory function at six months in individuals infected with the coronavirus disease 2019 omicron variant, using psychophysical tests.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215123000877_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A prospective case\u2013control study that included severe acute respiratory syndrome coronavirus-2 patients infected in February and March 2022 was conducted. Patients underwent the Sniffin\u2019 Sticks test within 10 days of infection and again after at least 6 months. The olfactory scores were compared with those of a control group.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215123000877_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>In all, 102 patients and 120 controls were enrolled in the study. At baseline, 26 patients (25.5 per cent) self-reported smell loss. The median threshold, discrimination and identification score was 33.6 (interquartile range, 12.5) for the cases and 36.5 (interquartile range, 4.38) for the controls (<jats:italic>p<\/jats:italic> &lt; 0.001). Based on the threshold, discrimination and identification scores, 12 controls and 34 patients reported olfactory dysfunction (<jats:italic>p<\/jats:italic> &lt; 0.001). Eighty cases underwent re-evaluation at six months; the median threshold, discrimination and identification score was 37.1 (interquartile range, 4.75) with no significant differences compared with the controls.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215123000877_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>Six months after infection, the prevalence of olfactory dysfunction in patients did not differ significantly from the control population.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215123000877","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T08:12:53Z","timestamp":1684311173000},"page":"1395-1400","source":"Crossref","is-referenced-by-count":3,"title":["Olfactory recovery following omicron variant infection: a psychophysical prospective case\u2013control study with six-month follow up"],"prefix":"10.1017","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7789-145X","authenticated-orcid":false,"given":"Luigi Angelo","family":"Vaira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Boscolo-Rizzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0845-0845","authenticated-orcid":false,"given":"Jerome R","family":"Lechien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1829-6597","authenticated-orcid":false,"given":"Miguel","family":"Mayo-Y\u00e1\u00f1ez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzia","family":"Petrocelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Pistidda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Salzano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Maglitto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Hopkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"De Riu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,5,17]]},"reference":[{"key":"S0022215123000877_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2021.103301"},{"key":"S0022215123000877_ref31","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-022-00511-0"},{"key":"S0022215123000877_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13564"},{"key":"S0022215123000877_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0173-0"},{"key":"S0022215123000877_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22995"},{"key":"S0022215123000877_ref34","first-page":"517","article-title":"High prevalence of long-term olfactory, gustatory, and chemesthesis dysfunction in post-COVID-19 patients: a matched case-control study with one-year follow-up using a comprehensive psychophysical evaluation","volume":"59","author":"Boscolo-Rizzo","year":"2021","journal-title":"Rhinology"},{"key":"S0022215123000877_ref35","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-020-03367-7"},{"key":"S0022215123000877_ref33","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29964"},{"key":"S0022215123000877_ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-022-07431-6"},{"key":"S0022215123000877_ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06868-5"},{"key":"S0022215123000877_ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2022.103667"},{"key":"S0022215123000877_ref40","first-page":"26","article-title":"Six month follow-up of self-reported loss of smell during the COVID-19 pandemic","volume":"59","author":"Hopkins","year":"2021","journal-title":"Rhinology"},{"key":"S0022215123000877_ref56","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30101"},{"key":"S0022215123000877_ref49","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215120002455"},{"key":"S0022215123000877_ref44","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22610"},{"key":"S0022215123000877_ref14","unstructured":"14 Overview of Variants in Countries. 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