{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:07:33Z","timestamp":1787170053397,"version":"build-2736575974"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T00:00:00Z","timestamp":1687132800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215123001147_sec_a1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Acute and chronic tonsillitis are frequently treated with antibiotics. This study aimed to understand the presence of pathogenic micro-organisms on the surface and core of chronically infected tonsils among Tanzanian children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215123001147_sec_a2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study enrolled children undergoing adenotonsillectomy. Surface and core tonsillar swabs were taken. Quantitative polymerase chain reaction was performed for\n                      <jats:italic>Streptococcus pneumoniae<\/jats:italic>\n                      ,\n                      <jats:italic>Haemophilus influenzae<\/jats:italic>\n                      ,\n                      <jats:italic>Moraxella catarrhalis<\/jats:italic>\n                      ,\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      ,\n                      <jats:italic>Neisseria meningitidis<\/jats:italic>\n                      and\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215123001147_sec_a3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Surface and core combined, isolated\n                      <jats:italic>N meningitidis<\/jats:italic>\n                      (86.1 per cent) was found the most, followed by\n                      <jats:italic>H influenzae<\/jats:italic>\n                      (74.9 per cent),\n                      <jats:italic>S pneumoniae<\/jats:italic>\n                      (42.6 per cent) and\n                      <jats:italic>S aureus<\/jats:italic>\n                      (28.7 per cent).\n                      <jats:italic>M catarrhalis<\/jats:italic>\n                      and\n                      <jats:italic>P aeruginosa<\/jats:italic>\n                      were only found in a few patients, 5.6 per cent and 0.8 per cent respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215123001147_sec_a4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Colonisation of the tonsillar surface and core has been found. Potentially pathogenic micro-organisms are likely to be missed based on a throat swab. Hence, the practice of surface tonsillar swabbing may be misleading or insufficient.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215123001147","type":"journal-article","created":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T01:04:46Z","timestamp":1687136686000},"page":"89-92","source":"Crossref","is-referenced-by-count":4,"title":["Bacterial colonisation of surface and core of palatine tonsils among Tanzanian children with recurrent chronic tonsillitis and obstructive sleep apnoea who underwent (adeno)tonsillectomy"],"prefix":"10.1017","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0771-9192","authenticated-orcid":false,"given":"Denis R","family":"Katundu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desderius","family":"Chussi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christa E","family":"van der Gaast-de Jongh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maroeska M","family":"Rovers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marien I","family":"de Jonge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerjon","family":"Hannink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"van Heerbeek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,6,19]]},"reference":[{"key":"S0022215123001147_ref19","doi-asserted-by":"publisher","DOI":"10.3126\/hren.v12i3.15252"},{"key":"S0022215123001147_ref26","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.1996.50"},{"key":"S0022215123001147_ref30","doi-asserted-by":"publisher","DOI":"10.1136\/postgradmedj-2018-135602"},{"key":"S0022215123001147_ref7","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00129-10"},{"key":"S0022215123001147_ref21","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10121560"},{"key":"S0022215123001147_ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-019-3830-5"},{"key":"S0022215123001147_ref29","doi-asserted-by":"crossref","first-page":"408238","DOI":"10.1155\/2013\/408238","article-title":"Evidence of bacterial biofilms among infected and hypertrophied tonsils in correlation with the microbiology, histopathology, and clinical symptoms of tonsillar diseases","volume":"2013","author":"Alasil","year":"2013","journal-title":"Int J Otolaryngol"},{"key":"S0022215123001147_ref17","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2022.42.142.35540"},{"key":"S0022215123001147_ref28","doi-asserted-by":"crossref","first-page":"2975","DOI":"10.12816\/0042838","article-title":"Causes and treatment of tonsillitis","volume":"69","author":"Saad","year":"2017","journal-title":"Egypt J Hosp Med"},{"key":"S0022215123001147_ref24","first-page":"MC01","article-title":"Anaerobic bacteriological microbiota in surface and core of tonsils in chronic tonsillitis","volume":"10","author":"Khadilkar","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"S0022215123001147_ref4","doi-asserted-by":"publisher","DOI":"10.14260\/jemds\/2018\/745"},{"key":"S0022215123001147_ref33","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5406467"},{"key":"S0022215123001147_ref11","first-page":"103","article-title":"Antibiotic prescribing practice in management of cough and\/or diarrhoea in Moshi Municipality, Northern Tanzania: cross-sectional descriptive study","volume":"12","author":"Gwimile","year":"2012","journal-title":"Pan Afr Med J"},{"key":"S0022215123001147_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-3904-x"},{"key":"S0022215123001147_ref14","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215109991939"},{"key":"S0022215123001147_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2017.07.003"},{"key":"S0022215123001147_ref23","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.11.1177"},{"key":"S0022215123001147_ref3","first-page":"271","article-title":"Comparative study of bacteriology in recurrent tonsillitis among children and adults","volume":"47","author":"Loganathan","year":"2006","journal-title":"Singapore Med J"},{"key":"S0022215123001147_ref6","first-page":"161","article-title":"Discrepancy between tonsillar surface and core culture in children with chronic tonsillitis and incidence of post tonsillectomy bacteraemia","volume":"9","author":"Elsherif","year":"2011","journal-title":"Al-Azhar Assiut Med J"},{"key":"S0022215123001147_ref20","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28403"},{"key":"S0022215123001147_ref2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6815-12-13"},{"key":"S0022215123001147_ref1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100108370"},{"key":"S0022215123001147_ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-021-06996-7"},{"key":"S0022215123001147_ref27","doi-asserted-by":"publisher","DOI":"10.47210\/bjohns.2017.v25i2.119"},{"key":"S0022215123001147_ref10","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.16.176123"},{"key":"S0022215123001147_ref31","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-21744-4_10"},{"key":"S0022215123001147_ref25","first-page":"1948","article-title":"Chronic tonsillitis bacteriology in Egyptian children including antimicrobial susceptibility","volume":"3","author":"Hammouda","year":"2009","journal-title":"Aust J Basic Appl Sci"},{"key":"S0022215123001147_ref12","doi-asserted-by":"crossref","first-page":"e0206623","DOI":"10.1371\/journal.pone.0206623","article-title":"Prevalence, determinants and knowledge of antibacterial self-medication: a cross sectional study in North-eastern Tanzania","volume":"13","author":"Kumburu","year":"2018","journal-title":"PLoS One"},{"key":"S0022215123001147_ref15","doi-asserted-by":"publisher","DOI":"10.3109\/00016486709128779"},{"key":"S0022215123001147_ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075558"},{"key":"S0022215123001147_ref5","first-page":"1390","article-title":"Chronic tonsillitis: a comparative study of the causative organism cultured through throat swab vs. core culture and biopsy of the tonsillectomy specimen","volume":"5","author":"Panga","year":"2016","journal-title":"Int J Sci Res"},{"key":"S0022215123001147_ref32","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31814543c8"},{"key":"S0022215123001147_ref22","first-page":"e3343","article-title":"Microbiological profile of chronic tonsillitis in the pediatric age group","volume":"10","author":"Kalaiarasi","year":"2018","journal-title":"Cureus"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215123001147","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T07:53:24Z","timestamp":1733212404000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215123001147\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,19]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S0022215123001147"],"URL":"https:\/\/doi.org\/10.1017\/s0022215123001147","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,19]]}}}